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Systemic Immune-Inflammatory Index and Other Inflammatory Marker Variations in Oral Squamous Cell Carcinoma Management.
Medicina (Kaunas)
November 2024
Department of Anesthesiology and Oral Surgery, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
: With the greatest rate of morbidity and death, OSCC is one of the world's most critical public health problems. Being a complex pathology, the management process that includes diagnostic, surgical, and adjuvant treatments must as well take into account the involvement of the immune system. This study aims to evaluate various biomarkers such as neutrophils, lymphocytes, platelets, SII, and NLR in the different stages of OSCC treatment and in correlation with TNM stages, in order to observe the inflammatory response of the host.
View Article and Find Full Text PDFDomain transformation using semi-supervised CycleGAN for improving performance of classifying thyroid tissue images.
Int J Comput Assist Radiol Surg
November 2024
Department of Artificial Intelligence Diagnostic Radiology, Graduate School of Medicine, Osaka University, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Purpose: A large number of research has been conducted on the classification of medical images using deep learning. The thyroid tissue images can be also classified by cancer types. Deep learning requires a large amount of data, but every medical institution cannot collect sufficient number of data for deep learning.
View Article and Find Full Text PDFA Second Ductoscopy Procedure in Patients with Recurrent and Persistent Pathological Nipple Discharge.
Breast Care (Basel)
August 2023
Department of Surgical Oncology, University Medical Center, Utrecht, The Netherlands.
Background: Most patients suffering from pathological nipple discharge (PND) undergo local surgical procedures because standard radiological imaging often fails to reveal the cause. Ductoscopy is a minimally invasive endoscopic technique that enables direct intraductal visualization and can avoid unnecessary diagnostic surgical procedures. Hence, patients with recurrent or persistent PND after an unsuccessful ductoscopy procedure still undergo unnecessary surgery.
View Article and Find Full Text PDFFlat intraurothelial lesions of the urinary bladder-do hyperplasia, dysplasia, and atypia of unknown significance need to exist as diagnostic entities? and how to handle in routine clinical practice.
Mod Pathol
October 2022
Departments of Pathology and Laboratory Medicine and Urology, University of Tennessee Health Science Center, Memphis, TN, USA.
Classification of the putative flat preneoplastic and neoplastic lesions of the urothelium with features subthreshold for urothelial carcinoma in situ remains a challenging, indeed, vexing problem in diagnostic surgical pathology. This area, subtending lesions including flat urothelial hyperplasia, urothelial dysplasia, and atypia of unknown significance, has struggled under evolving classifications, changing criteria, and limited clinical actionability, all confounded by the recognized lack of diagnostic reproducibility. Herein, we review the state of the literature around these lesions, reviewing contemporary criteria and definitions, assessing the arguments in favor and against of retaining hyperplasia, dysplasia, and atypia of unknown significance as diagnostic entities.
View Article and Find Full Text PDFThymic Carcinoma: A Review.
Front Oncol
April 2022
Department of Pathology, MD Anderson Cancer Center, University of Texas, Houston, TX, United States.
The diagnosis of thymic carcinoma may pose significant problems not necessarily in the histopathological diagnosis but rather in assigning the thymus as specific origin. Often the tissue available for interpretation is obtained a mediastinocopic biopsy, which raises two different issues -minimal tissue and lack of specific features to make a carcinoma of thymic origin. In addition, if to that conundrum we add that there is no magic immunohistochemical stain that will unequivocally lead to the interpretation of thymic carcinoma, then we are left with a true clinical-radiological-pathological correlation.
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