Dun Hua is a district where endemic goiter has been prevalent. Residents commenced to eat iodined salt ten years ago. We studied 469 people in this district and discovered that the incidence of endemic goiter had somehow come down but still kept 10.4%. However, the incidence of thyroid cancer went up to 1.9% with the incidence of thyroiditis 0.85%. Pathological characteristic of endemic goiter frequently appeared adenoniatoid feature with some atypical hyperplasia follicles which facilitates the cancerization in the fibrigenic part. Reasons accounted for the endemic goiter occurrance might not only relate to the insufficient intake of iodined salt but also to the increase of iodine excretion from the body. The increase of iodine excretion may be related to the factors as varieties of subsidiary food and vegetables as well as personal habitualness on food and drinks.

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