Background And Aims: Cardiovascular disease is the major cause of death in over 60-year-old women. The mean age of onset is about 10 years later in women compared to men, a difference which can be explained by the end of physiological estrogen production in menopause.
Methods: The authors treated a group of 68 menopausal patients with HRT for a period of 5 years.
Results: A series of positive effects emerged from the study which were potentially capable of preventing ischemic cardiopathy.
Conclusions: The authors reached the conclusion that--owing to its beneficial effects on lipid and glucose metabolism, as well as on coagulation factors and arterial pressure--HRT is able to prevent cardiovascular disease, reducing the risk of infarction by between 20 and 50%.
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