A complex histochemical, morphometric and immunohistochemical study of communication systems, i.e. histophysiological clusters of vegetative nervous terminals, the microcirculatory bed and their immediate cellular microenvironments has been conducted. It was found that the structural and functional characteristics of communication systems play a significant role in the development of morphogenesis of stromal component of breast cancer and, therefore, may be used as a criterion of individual prognosis.

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