From 1953 through 1955 a total of 2364 individuals between o and 18 years were discharged from the Stockholm Child Guidance Clinics. Among these patients 125 (68 boys, 57 girls) were under the age of 3 years. A follow-up study was conducted 30 years later on this sample using records from psychiatric clinics and data from official registers of problematic behaviours. The majority of the infants when seen at the Child Guidance Clinics were judged to be mentally healthy or to have shown mild environmental reactions. However sixty per cent of these patients were identified in at least one of the registers during the follow-up period. Thus the initial evaluation was not prognostic of the future development. Boys developed mainly social maladjustment, whereas girls more often applied for psychiatric care during the follow-up. Significant prognostic factors in the 1950s were gender and parental psychiatric diagnosis.
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Mol Pharm
January 2025
School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China.
Early detection and precise treatment for breast cancer are crucial, given its high global incidence rate. Hence, the development of novel imaging targets is essential for diagnosing and monitoring resistance to chemotherapy, which is pivotal for achieving precise and personalized treatment for breast cancer patients. In our previous work, we successfully developed a near-infrared (NIR) probe for CYP1B1-targeted imaging.
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January 2025
Manipal Academy of Higher Education, Manipal, Karnataka, India.
Background: Most children experience distress while visiting a dentist, above which the sound of the airotor and suction machine results in fear and difficulty in performing further procedures.
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BMC Med Genomics
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Ultrasound Diagnosis Department, Maternal and Child Health Hospital of Hubei Province, Wuhan, 430070, China.
Background: The clinical manifestations of PI4KA-related disorders are characterized by considerable variability, predominantly featuring neurological impairments, gastrointestinal symptoms, and a combined immunodeficiency. The aim of this study was to delineate the novel spectrum of PI4KA variants detected prenatally and to assess their influence on fetal development.
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Sci Rep
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Department of Biochemistry and Molecular Biology, Shanxi Key Laboratory of Birth Defect and Cell Regeneration, Key Laboratory of Coal Environmental Pathogenicity and Prevention (Ministry of Education, China, Shanxi Medical University, No. 56, Xinjian South Road, Yingze District, Taiyuan City, 030000, Shanxi Province, China.
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