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Cognitive reserve predicts long-term cognitive trajectories in relapsing-remitting multiple sclerosis.
Mult Scler
December 2024
Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli," Naples, Italy.
Background: The effect of cognitive reserve (CR) on cognition in people with relapsing-remitting multiple sclerosis (pwRRMS) has been partially investigated.
Objectives: We aimed to explore the long-term cognitive trajectories of pwRRMS based on their CR, measured using the Vocabulary Knowledge Test (VOC).
Methods: 78 pwRRMS underwent a neuropsychological evaluation at baseline and after a mean follow-up of 6.
Childhood and Adulthood Predictors of Community Participation by Autistic Adults With and Without Intellectual Disability.
J Appl Res Intellect Disabil
January 2025
Centre for Developmental Psychiatry and Psychology, Department of Psychiatry, School of Clinical Sciences at Monash Health, Monash University, Clayton, Australia.
Background: Few studies have explored community participation for autistic adults, with or without intellectual disability. This study aims to investigate how autistic adults participate in the community, and the childhood and adulthood factors that predict community participation in adulthood.
Method: Eighty-four autistic adults (mean age 34 years; 67% with co-occurring intellectual disability) initially recruited as children and adolescents, participated in the current study.
The differential diagnostic utility of the social communication questionnaire in mild intellectual disability and autism spectrum disorder: a case control study.
Int J Dev Disabil
August 2024
Department of Child and Adolescent Psychiatry, Faculty of Medicine, Selcuk University, Konya, Turkey.
Objectives: This study investigated the utility of specific predictive and discriminative items within the Social Communication Questionnaire (SCQ) for distinguishing between autism spectrum disorder (ASD), intellectual disability (ID), and co-occurring ASD + ID in children.
Methods: A total of 137 children aged 4 to 12 years (52 typically developing (TD), 34 ASD, 26 ID, 25 ASD + ID) were included in the study. Cognitive development assessments were conducted for the ASD, ID, and ASD + ID groups in suitable cases.
Satisfying basic psychological needs through a recreational sports programme for people with intellectual disability: human growth and adapted sport in focus.
Front Psychol
December 2024
Faculty of Education, University of A Coruña, A Coruña, Spain.
Introduction: Self-determination theory (SDT) highlights the importance of satisfying people's basic psychological needs (BPN) (autonomy, competence and relatedness) in order to ensure their personal growth and wellbeing. In this regard, sport and physical activity (PA) have been shown to offer significant health benefits, particularly in the case of people with intellectual disability (ID), among whom the benefits are even more noticeable owing to their low levels of PA, sedentary lifestyle, limited opportunities to exercise, and consequently lower quality of life. The aim of this study is to assess the impact of the Más Que Tenis ("More Than Just Tennis") inclusive recreational sports programme on the satisfaction of BPN among athletes with ID, taking into account factors such as age, gender and type of activity.
View Article and Find Full Text PDFDifferential Infiltration of Key Immune T-Cell Populations Across Malignancies Varying by Immunogenic Potential and the Likelihood of Response to Immunotherapy.
Cells
December 2024
Departments of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Solid tumors vary by the immunogenic potential of the tumor microenvironment (TME) and the likelihood of response to immunotherapy. The emerging literature has identified key immune cell populations that significantly impact immune activation or suppression within the TME. This study investigated candidate T-cell populations and their differential infiltration within different tumor types as estimated from mRNA co-expression levels of the corresponding cellular markers.
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