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Application of low-intensity anticoagulation after On-X mechanical aortic valve replacement.
J Cardiothorac Surg
January 2025
Cardiac Surgery Center, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Affiliated Hospital of University of Electronic Science and Technology, Chengdu, Sichuan Province, 610072, China.
Objective: To explore the safety and efficacy of low-intensity anticoagulation in patients after On-X mechanical aortic valve replacement.
Methods: A total of 104 patients undergoing aortic valve replacement in Cardiac Surgery Department of Sichuan Provincial People's Hospital from December 2018 to December 2021 were randomly divided into low-intensity anticoagulant (INR:1.5-2.
Computational study on water based hybrid photovoltaic systems with different absorber configurations.
Sci Rep
January 2025
Department of Mechanical Engineering, India KLS Vishwanathrao Deshpande Institute of Technology, Haliyal, India.
The current study assesses several water-based PVT system thermal absorber configurations. The thermal absorber in PVT system plays a vital role in efficiency evaluation as it lowers PV temperature and collects heat energy. The current study aims to discover and analyze advanced thermal absorber design by comparing well-received spiral circular absorbers and non-cooled PV with proposed semi-circular thermal absorbers with varying flow configurations.
View Article and Find Full Text PDFAssociations between paraoxonase-1 activity and therapeutic drug monitoring indicators in schizophrenia patients treated with olanzapine: A cross-sectional study.
J Psychopharmacol
January 2025
Psychiatric Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Objective: Therapeutic drug monitoring (TDM) indicators have been suggested to predict overall outcome responses to olanzapine (OLZ) treatments in terms of efficacy and metabolic syndrome. This study aimed to investigate whether paraoxonase-1 (PON-1) activity can be used to predict schizophrenia patient outcomes.
Methods: Schizophrenic patients ( = 50) aged between 20 and 65 years who received OLZ treatment were recruited, and their Positive and Negative Syndrome Scale scores, PON-1 activity, and olanzapine drug levels normalized by dose (OLZ/D) and its metabolite N-desmethyl-olanzapine (DMO), together with biochemical parameters, were determined.
A NIRS-Based Technique for Monitoring Brain Tissue Oxygenation in Stroke Patients.
Sensors (Basel)
December 2024
Division of Neurological Rehabilitiation, Instituto Nacional de Rehabilitacion Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.
Stroke is a global health issue caused by reduced blood flow to the brain, which leads to severe motor disabilities. Measuring oxygen levels in the brain tissue is crucial for understanding the severity and evolution of stroke. While CT or fMRI scans are preferred for confirming a stroke due to their high sensitivity, Near-Infrared Spectroscopy (NIRS)-based systems could be an alternative for monitoring stroke evolution.
View Article and Find Full Text PDFAn end-to-end implicit neural representation architecture for medical volume data.
PLoS One
January 2025
NCCA, Bournemouth University, Poole, United Kingdom.
Article Synopsis
- Medical volume data is increasing significantly, leading to challenges in organizing, storing, and processing large datasets.
- The proposed solution is an end-to-end architecture for data compression using deep learning, featuring modules for downsampling, implicit neural representation, and super-resolution.
- Experimental results show impressive compression rates of up to 97.5% while preserving high reconstruction quality, making it efficient for managing large medical data on GPUs.
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