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http://dx.doi.org/10.1016/s0929-693x(98)80112-7DOI Listing

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Objectives: To identify what changes in the prescribing of isotretinoin have occurred since funded prescriber access was widened in 2009 from 'dermatologist only' prescribing to include 'general practitioners (GPs) and nurse practitioners working within their scope of practice'.

Design: Evaluation of isotretinoin dispensing data from 2008 to 2023 using the national annual prescribing data obtained from the New Zealand Pharmaceutical National Collection database.

Setting: All New Zealand citizens prescribed and dispensed funded isotretinoin for acne from 2008 to 2023 were included.

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A comparison of iPLEDGE requirements to risk mitigation programs for isotretinoin in other countries and to other teratogenic medications in the United States.

J Am Acad Dermatol

January 2025

The George Washington University School of Medicine and Health Sciences, Department of Dermatology, Washington, DC 20052; Children's National Hospital, Division of Dermatology, Washington, DC 20010.

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Background: Acne is an inflammatory skin disease afflicting the majority of the world's population at some point in their lifetime, and is seen to be chronic in about 50% of cases. Acne leads to significant social withdrawal, depression, and disfiguring scars in many cases. Available treatments are characterized by high rates of relapse, dangerous side effects, and social stigma, which often leads to poor patient compliance and treatment failure.

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Article Synopsis
  • This review analyzes the effects of oral retinoids like isotretinoin on wound healing across different surgical fields.
  • It raises concerns about the common practice of stopping these medications before surgery, suggesting it's not always necessary based on current research.
  • The article calls for personalized decisions regarding retinoid use before surgery and highlights the importance of collaboration between dermatologists and surgeons for better perioperative care.
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Maintenance Acne Treatment with Topical Tazarotene after Oral Isotretinoin: Overview and Case Reports.

J Clin Aesthet Dermatol

January 2024

Ms. Miranti is with Riverchase Dermatology and Cosmetic Surgery in Naples, Florida.

Acne is a chronic dermatologic disorder that can require long-term treatment. To prevent recurrence after oral treatment for severe acne, topical maintenance treatment is recommended; however, there is little guidance or research on maintenance regimens. This article briefly summarizes literature on oral isotretinoin and topical retinoids and presents a case series of patients who received tazarotene 0.

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