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Lichenoid paraneoplastic pemphigus in a patient presenting with follicular lymphoma: a review of the literature.
Arch Dermatol Res
November 2024
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1295 NW 14th St, Miami, FL, 33125, USA.
Article Synopsis
- Paraneoplastic pemphigus (PNP) is a rare autoimmune blistering disease linked to cancer, typically presenting with severe mouth sores and varied skin eruptions.
- The case study details a patient with follicular lymphoma (FL) who developed symptoms of PNP, prompting a review of current treatment options and understanding of the disease.
- Despite potential remission from related cancers, PNP has a low 5-year survival rate, highlighting the urgent need for more research and suggesting that T cell immunosuppressive therapy might help FL patients with PNP.
Histopathologic Comparisons of Discoid Lupus Erythematosus and Folliculotropic Mycosis Fungoides in a Series of 43 Cases.
J Cutan Pathol
November 2024
Oakland University William Beaumont School of Medicine, Rochester Hills, Michigan, USA.
Background: Folliculotropic mycosis fungoides (FMF) is a rare cutaneous malignancy that can be mistaken for inflammatory diseases, such as discoid lupus erythematosus (DLE), due to the variability of histopathological findings.
Methods: This study aims to provide dermatopathologists with evidence-based histopathologic criteria to distinguish DLE from FMF by reporting overlapping and distinguishing microscopic features. Forty-three biopsies from patients with a confirmed diagnosis of DLE or FMF were graded for the presence or absence of 18 histopathologic features.
Uncommon and Unusual Variants of Autoimmune Bullous Diseases.
Indian Dermatol Online J
August 2024
Department of Dermatology, Venereology and Leprology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Article Synopsis
- Autoimmune blistering diseases (AIBDs) are skin conditions caused by the body's immune system attacking certain proteins, leading to blister formation, and can be categorized into intraepidermal and subepidermal types.
- The objective of this review is to raise awareness about rare and uncommon AIBD variants, such as pemphigus herpetiformis and anti-laminin 332 pemphigoid, among others.
- By discussing these unusual variants, the review aims to assist healthcare professionals in the early diagnosis and treatment of these conditions.
Photodistributed Lichenoid Eruption with Alopecia: A Unique Presentation of Graham-Little-Piccardi-Lasseur Syndrome.
Int J Trichology
April 2024
Department of Dermatology, Kansas City University, Kansas, Florida, USA.
Article Synopsis
- Graham-Little-Piccardi-Lasseur syndrome (GLPLS) involves widespread hair loss and a specific skin rash on the scalp and other areas of the body, and is linked to lichen planopilaris.
- The condition typically begins with thick skin bumps and leads to hair loss, and while other forms of lichen planus can show reactions to sunlight, GLPLS had not been previously documented with such an eruption.
- This report introduces the first case of GLPLS with a sun-related rash, discussing its underlying causes and treatment options.
A Saudi Woman with Ceftriaxone Induced Fixed Drug Eruption.
Case Rep Dermatol Med
March 2024
School of Health Sciences, University of Salford, Manchester, UK.
Background: A fixed drug eruption (FDE) is an immunological cutaneous adverse reaction, classified as a cutaneous adverse drug reaction (CADR) and characterized by well-defined lichenoid lesions that occur at the same site each time. Ceftriaxone is a third-generation antibiotic of cephalosporin antibiotics of the beta-lactam antibiotic family, which has typical activity against many Gram-negative aerobic bacteria. This is the first clinical case from Saudi Arabia and the fifth in the world to document a woman's experience with recurrent FDE after repeated ceftriaxone use.
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