This study investigated the psychiatric consequences of 38 consecutive patients who had surgery for intractable temporal lobe epilepsy with special attention to postoperative mood disorders. A close interrelation between preoperative postictal psychosis and postoperative manic or depressive episodes was suggested. Left sided lobectomy augmented this correlation. Because the first sign of postoperative manic and depressive episodes appeared within 1 month and 2 months respectively, cautious psychiatric follow up for several months after surgery proved to be crucial to prevent postoperative suicides. Postoperative manic depressive episodes disappeared within the first 2 years after operation without exception, if treated suitably. This suggests that we do not have to preclude patients with postictal psychosis as surgical candidates, but measures must be taken to prevent postoperative depressions.
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http://dx.doi.org/10.1136/jnnp.65.4.587 | DOI Listing |
Cureus
December 2024
Department of Psychiatry, Louisiana State University Health Sciences Center, Shreveport, USA.
Rev Prat
November 2024
Service de psychiatrie, université de Lorraine et service de neurologie, hôpital central de Nancy, Nancy, France.
EPILEPSY AND PSYCHIATRIC DISORDERS (EPI-PSY). Epilepsy is not only a brain pathology characterized by a lasting predisposition to generate seizures, it is also associated with cognitive, behavioral, psychological, and social disorders. The interaction between psychiatric pathologies and epilepsy is bidirectional and complex.
View Article and Find Full Text PDFEpilepsy Behav Rep
October 2024
Department of Neurology, Wake Forest University School of Medicine, United States.
Epilepsia
December 2024
Division of Psychiatry, University College London, London, UK.
Individuals with epilepsy are at risk of developing preictal, ictal, postictal and interictal psychoses. Antipsychotic drugs (APDs) are the main class of drugs used to treat psychosis and schizophrenia. The efficacy and safety of APDs as a treatment for epileptic psychosis is not well understood.
View Article and Find Full Text PDFSeizure
October 2024
EEG-monitoring Unit, Neurology Department, Hôpital Central, CHU de Nancy, 54000 Nancy, France; Pôle Universitaire du Grand Nancy, Centre Psychothérapique de Nancy, 54000 Laxou, France.. Electronic address:
Multiple hypotheses exist about the pathophysiology of Postictal Psychosis (PIP). As the clinical manifestations of PIP are roughly stereotyped, we assumed the existence of a common neurological pathway. This study aimed to determine if a specific brain network sustained the psychotic episode, regardless of the localization of the epileptogenic zone.
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