Donor site morbidity for free fibula microvascular flaps is generally reported to be low and considered to be minor. We describe a case where the major complication of compartment syndrome occurred in a 15-year-old boy when the donor site defect was closed primarily after taking a skin paddle with a width of 4 cm. We recommend that when harvesting free fibula flaps in children, skin grafting of donor site should be considered irrespective of the width of the flap, if there is any doubt about the tightness of the closure.
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http://dx.doi.org/10.1054/bjps.1998.0005 | DOI Listing |
Cell Mol Life Sci
March 2025
Institute for Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Medizinisch-Theoretisches Zentrum MTZ, Technische Universität Dresden, Fiedlerstraße 42, 01307, Dresden, Germany.
Signal peptide peptidase (SPP) is an ER-resident aspartyl intramembrane protease cleaving proteins within type II-oriented transmembrane segments. Here, we identified the tail-anchored protein Three prime repair exonuclease 1 (TREX1) as a novel substrate of SPP. Based on its DNase activity, TREX1 removes cytosolic DNA acting as a negative regulator of the DNA-sensing cGAS/STING pathway.
View Article and Find Full Text PDFJ Phys Chem B
March 2025
Department of Chemistry, University of Rome Sapienza, Rome 00185, Italy.
We present a structural characterization of a low-transition-temperature mixture (LTTM), consisting of thymol and carvacrol, at an equimolar ratio. Carvacrol and thymol are natural regioisomers of terpenes. When combined at an equimolar ratio, they form a liquid mixture at room temperature, with supercooling capability and glass transition at ca.
View Article and Find Full Text PDFSwiss Dent J
March 2025
Riga Stradiņš University, Faculty of Dentistry.
Autotransplantation of immature third molars is an effective treatment option, offering high success rates, minimal complications, and notable improvements in occlusal function and dental aesthetics. This study aims to review and evaluate the available evidence specifically on the survival and success rates of immature autotransplanted third molars and to identify prognostic factors that influence these outcomes. A comprehensive search was conducted in the Elsevier Journals (ScienceDirect), MEDLINE (PubMed), and Dentistry & Oral Sciences Source (EBSCOhost) databases up to May 2024.
View Article and Find Full Text PDFJ Craniofac Surg
March 2025
Michael E. DeBakey Department of Surgery, Division of Plastic Surgery, Baylor College of Medicine.
Introduction: Traditionally, alveolar bone grafting (ABG) uses bone from the iliac crest for repair. Harvesting this graft has been associated with significant donor site pain. Local anesthetic is a useful adjunct to alleviate postoperative opioid requirements.
View Article and Find Full Text PDFFront Surg
February 2025
Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital Basel, Basel, Switzerland.
Introduction: Costochondral grafting is well-known reconstructive option for the temporomandibular joint. In the upper extremity, non-vascularized costochondral grafts have been used for radial head reconstruction, for osteoarthritis of the trapeziometacarpal joint and proximal pole reconstruction of the scaphoid. Evidence suggests that vascularization of bone grafts lead to a higher union rate and a faster time to union.
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