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Early Alterations of Cytoskeletal Proteins Induced by Radiation Therapy in the Parenchymal Cells of Rat Major Salivary Glands: A Comparative Immunohistochemical Analysis.
Cureus
December 2024
Department of Basic and Clinical Oral Sciences, Umm Al-Qura University, Makkah, SAU.
Objectives: Head and neck malignancies (HNMs) encompass a variety of cancers that affect the oral and para-oral tissues, the most common of which are squamous cell carcinomas. Radiotherapy is commonly used to treat these cancers, often involving radiation exposure to the salivary glands. This study aims to investigate the early impacts of radiotherapy on the internal microstructure of the salivary gland cells and identify which gland exhibits the highest level of radiosensitivity.
View Article and Find Full Text PDFLarge recurrent sialoliths in a residual Wharton duct after sialoadenectomy: Two case reports and literature review.
Medicine (Baltimore)
January 2025
Department of Oral and Maxillofacial Surgery.
Rationale: When gland-preserving treatments are unsuccessful, sialoadenectomy is typically conducted for patients afflicted with submandibular gland diseases. The definitive treatment modality for these individuals is the removal of both the gland and the associated ducts. During surgery, the gland and the majority of the ducts can be excised utilizing the lateral transcervical approach, with residual ducts unlikely to develop pathology.
View Article and Find Full Text PDFCT navigation-assisted intraoral extraction of large submandibular gland stones: a minimally invasive approach.
J Surg Case Rep
January 2025
Otolaryngology Department, İzmir Bozyaka Training and Research Hospital, İzmir City Hospital, Bahar, Saim Çıkrıkçı Cd. No: 59, 35170 Karabağlar, Izmir, Turkey.
Sialolithiasis is a common cause of salivary gland obstruction, leading to symptoms such as pain and swelling. In cases of intraparenchymal submandibular stones and proximal ductal stones larger than 7 mm, interventional sialendoscopy may fail, necessitating sialoadenectomy. As an alternative, intraoral stone extraction can be performed with CT-guided navigation.
View Article and Find Full Text PDFSalivary pH, but not conductivity, is an indicator of diarrhea in neonatal calves.
Front Vet Sci
December 2024
Scotland's Rural College (SRUC), Edinburgh, United Kingdom.
Article Synopsis
- Neonatal calf diarrhea frequently leads to dehydration and metabolic acidosis, impacting calf mortality, growth, and productivity, prompting interest in technological disease detection.
- The study explored the relationship between saliva conductivity and pH with clinical and biochemical indicators in calves, assessing the health of 141 dairy-bred calves from one week old until 25 days or until they developed diarrhea.
- Results indicated that while saliva pH decreased in calves with diarrhea, saliva conductivity showed no correlation with diarrhea or dehydration, highlighting the complexity of hydration status assessments in these animals.
Chronic stress triggers impairments of the redox status of salivary glands associated with different histological responses in rats.
Stress
December 2025
Laboratory of Functional and Structural Biology, Biological Sciences Institute, Federal University of Pará, Belém, Brazil.
Stress occurs as a reaction to mental and emotional pressure, anxiety, or scarring. Chronic stress is defined as constant submission to these moments. It can affect several body systems, increase blood pressure, and weaken immunity, thereby interfering with physiological health processes.
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