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The A-Z of age-related dermatological diseases.
Br J Community Nurs
January 2025
Freelance medical writer and journalist.
Skin ageing is an inevitable process influenced by both intrinsic and extrinsic factors. Intrinsic aging leads to thinner, drier and less elastic skin with fine wrinkles, while extrinsic factors such as sun exposure, smoking and environmental stresses amplify these changes. Photo-ageing, in particular, causes deep wrinkles, uneven pigmentation and increases the risk of skin cancers.
View Article and Find Full Text PDF[A case of Candida meningitis in a patient with CARD9 deficiency: an autopsy report].
Rinsho Shinkeigaku
September 2024
Department of Neurology, Hyogo Prefectural Amagasaki General Medical Center.
Article Synopsis
- A 23-year-old woman had a long history of fungal infections and started having headaches, leading doctors to analyze her cerebrospinal fluid (CSF), which showed a lot of immune cells.
- They found a fungus called Candida albicans in her CSF, which caused a type of brain infection called Candida meningitis, and gave her antifungal medication.
- Unfortunately, she didn't get better and suffered complications, leading to her death, and doctors later found out she had a rare genetic issue known as CARD9 deficiency, which can cause immune problems.
IL-17 serum level in patients with chronic mucocutaneous candidiasis disease.
Pediatr Allergy Immunol
January 2022
Department of Human Pathology of Adulthood and Childhood, Pediatric Emergency Unit, University of Messina, Messina, Italy.
Background: Chronic mucocutaneous candidiasis (CMC) is defined by recurrent or persistent superficial infections involving nails, skin, and/or oral and genital mucosae. IL-17 promotes the recruitment, chemotaxis, and expansion of neutrophils and acts directly on keratinocytes and epithelial cells, driving the production of antimicrobial peptides, essential for the immune response against Candida.
Aim: To evaluate the serum level of IL-17 in a family affected by CMC restricted to the nails of the hands and feet.
Onychomycosis in children: Safety and efficacy of antifungal agents.
Pediatr Dermatol
September 2018
School of Medicine, University of California, San Diego, CA, USA.
Onychomycosis is an uncommon condition in childhood, but prevalence in children is increasing worldwide.The objective was to review the efficacy and safety of systemic and topical antifungal agents to treat onychomycosis in children. Databases (Pubmed, OVID, Scopus, clinicaltrials.
View Article and Find Full Text PDFFungal infection of the nails is an increasingly recognized disease in infants and children. However, it can be difficult to distinguish clinically from other nail dystrophies. In addition, many mistakenly believe that onychomycosis does not occur in childhood.
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