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The jalap roots: A herbal legacy from the neotropics to the world.
J Ethnopharmacol
January 2025
Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510, Mexico City, Mexico. Electronic address:
Etnopharmacological Relevance: The Convolvulaceae or morning glory family, with about 2000 species in the world's Tropics and subtropics, stands out among the plants used in traditional medicine. Medicinal plant complexes with important purgative properties have been developed in Mexico and Brazil from members of the genera Ipomoea and Operculina with storage roots. Popularly known as the jalap roots, their resin glycosides cause purgative and laxative activities that facilitate bowel movements.
View Article and Find Full Text PDFDefining the needle in a haystack: A compendium of genomic, pathologic, and clinical characteristics of rare pulmonary tumors.
Lung Cancer
December 2024
Department of Internal Medicine, Division of Hematology/Oncology, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine (IUSOM), Indianapolis, IN 46202, USA. Electronic address:
A major paradigm shift in the diagnosis, management, and survival outcomes of early and advanced non-small cell lung cancer has transpired over the past few decades in thoracic oncology with the incorporation of molecular testing, targeted therapy, immunotherapy, neoadjuvant, and adjuvant approaches. However, transformation in the management and survival outcomes of rare lung tumors is lacking. Given the scarcity of these tumor types, randomized trials are rarely performed, and treatment is extrapolated from case series, tumor-agnostic trials, or cancers with similar histology.
View Article and Find Full Text PDFAdnexal masses: a compendium of established radiological signs.
Abdom Radiol (NY)
December 2024
Massachusetts General Hospital, Boston, USA.
Adnexal masses are frequently encountered in general practice. Whether employing CT, US, or MRI, imaging plays a pivotal role in guiding appropriate treatment for patients with adnexal masses, potentially minimizing the need for surgery in benign cases and expediting the management of those with suspected malignancy. Accurately distinguishing benign from malignant adnexal masses can be challenging due to the confined pelvic space and the proximity of organs, making it difficult to determine their organ of origin or to distinguish tissue characteristics and imaging features.
View Article and Find Full Text PDFBacteriology testing and antimicrobial resistance detection capacity of national tiered laboratory networks in sub-Saharan Africa: an analysis from 14 countries.
Lancet Microbe
January 2025
One Health Trust, Washington, DC, USA.
Background: Accurate detection of antimicrobial resistance (AMR) depends on adequate laboratory capacity. We aimed to document key weaknesses hindering AMR detection at various tiers of laboratory networks in 14 countries in sub-Saharan Africa, and analyse their significance in AMR surveillance and policies.
Methods: In this analysis, we obtained retrospective data on AMR and antimicrobial consumption from 14 countries participating in the Mapping Antimicrobial Resistance and Antimicrobial Use Partnership between May 1, 2019, and June 30, 2020.
Global natural and anthropogenic methane emissions with approaches, potentials, economic costs, and social benefits of reductions: Review and outlook.
J Environ Manage
January 2025
School of Engineering, Hangzhou Normal University, Hangzhou, 311121, China; College of Environmental and Resource Sciences, Zhejiang University, Hangzhou, 310058, China. Electronic address:
Article Synopsis
- * Human activities have significantly increased methane emissions by nearly 60% in the last 50 years, and natural emissions may rise due to climate change.
- * The text reviews methane emissions, evaluates reduction strategies and their costs and benefits, identifies challenges in achieving these reductions, and proposes potential future solutions.
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