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http://dx.doi.org/10.1016/s0003-4975(98)00700-0DOI Listing

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Background: Autologous fat grafting in the buttocks has gained great popularity However, one of the main risks is infiltration of fat into the systemic venous system, leading to potential complications such as macroscopic fatty embolism (MAFE), which can be fatal.

Objectives: This study evaluated the safety and efficacy of the LiRi (Linear Retrograde infiltration) for autologous fat grafting in the buttocks, and its evolution over a six-month follow-up period.

Methods: The procedure was performed in 114 patients.

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Background: Nerve wraps composed of various autologous and bioengineered materials have been used to bolster nerve repair sites. In this study, we describe the novel use of autologous fascia nerve wraps (AFNW) as an adjunct to epineurial repair and evaluate their effect on inflammatory cytokine expression, intraneural collagen deposition and end-organ reinnervation in rats and use of AFNW in a patient case series.

Methods: Lewis rats received sciatic transection with repair either with or without AFNW, sciatic-to-common peroneal nerve transfer with or without AFNW, or sham surgery (n=14/group).

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Complete talar extrusion is a rare injury that is typically caused by high-energy impact. Treatment for a completely extruded talus is limited and has variable outcomes and complications. Tibiocalcaneal arthrodesis is one of the best treatments for restoring stability and reducing pain in the affected limb.

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Transplantation of induced pluripotent stem cell-derived neural cells represents a promising strategy for treating neurodegenerative diseases. However, reprogramming of somatic cells and their subsequent neural differentiation is complex and time-consuming, thereby impeding autologous applications. Recently, direct transcription factor-based conversion of blood cells into induced neural stem cells (iNSCs) has emerged as a potential alternative.

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Article Synopsis
  • This study investigated the effects of retrograde autologous priming (RAP) on blood transfusion needs and hemodynamic stability in patients undergoing coronary artery bypass surgery (CABG), comparing 162 patients who received RAP to 281 who did not.
  • The results showed that the RAP group required significantly less blood transfusion and had shorter ICU stays, although 17% experienced hemodynamic instability that led to premature termination of the procedure.
  • Risk factors for hemodynamic instability were identified as body surface area (BSA) and baseline central venous pressure (CVP), with specific cutoff values that indicate higher sensitivity and specificity for predicting complications.
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