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The effect of lead (Pb) exposure and iron (Fe) deficiency on intestinal lactobacilli, E. coli and yeast: A study in experimental rats.
J Occup Health
November 2018
Drug Toxicology Division, ICMR - National Institute of Nutrition.
Objective: The current study investigated the additive effect of oral lead (Pb) exposure and dietary iron (Fe) deficiency on intestinal lactobacilli, E. coli, and yeast in SD rats.
Methods: Weanling rats were fed on control diet (CD) or iron deficient diet (ID) for 4 weeks, followed by oral Pb exposure for another 4 weeks.
Construction and evaluation of a O139 Vibrio cholerae vaccine candidate based on a hemA gene mutation.
Vaccine
May 2006
Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian 16150, Kelantan, Malaysia.
In this paper, we describe the development of VCUSM2, a live metabolic auxotroph of Vibrio cholerae O139. Auxotrophy was achieved by mutating a house keeping gene, hemA, that encodes for glutamyl-tRNA reductase, an important enzyme in the C5 pathway for delta-aminolevulenic acid (ALA) biosynthesis, which renders this strain dependent on exogenous ALA for survival. Experiments using the infant mouse and adult rabbit models show that VCUSM2 is a good colonizer of the small intestine and elicits greater than a four-fold rise in vibriocidal antibodies in vaccinated rabbits.
View Article and Find Full Text PDF[Clinical response to photodynamic therapy in premalignant lesions and advanced head and neck carcinomas].
Otolaryngol Pol
March 2004
Ośrodek Diagnostyki i Terapii Laserowej Katedry i Oddziału Klinicznego Chorób Wewnetrznych i Medycyny Fizykalnej Sl. AM w Katowicach.
The main advantage of PDT in laryngology seems to be its non-invasiveness and the possibility of using it despite of previous application of conventional methods. In the study application of PDT in two separated groups of patients, i.e.
View Article and Find Full Text PDFAim: To characterize patients with various nosological unities [symbol: see text] of porphyria in accordance with their age, clinical symptoms, provoking factors, therapy and outcome.
Material And Methods: Patients with acute intermittent porphyria (43), hereditary coproporphyria (8), variegate porphyria (3), porphyria cutanea tarda (7), hepatoerythropoietic porphyria (1), and hereditary erythropoietic porphyria (2) were studied. One patient was suspected of porphyria caused by deficiency of delta-aminolevulenic acid dehydrogenase.
delta-Aminolevulenic acid (ALA) and the control of intestinal iron absorption.
Biochem Soc Trans
August 1998
Department of Clinical Biochemistry, King's College School of Medicine and Dentistry, London.
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