This paper presents a case of multifocal metastases in the brain, which on the basis of typical imaging magnetic resonance and computerized tomography suggested possible parasitic changes (cerebral cysticercosis). On the basis of these pictures cerebral cysticercosis was diagnosed, in spite in the absence of serologic changes in blood and cerebrospinal fluid. The lack of improvement after anticysticercosis drugs, the further course of the disease as well as new foci located in other organs outside the brain, allowed to recognize numerous metastases in the brain although until the end of the clinical observation the primary lesion of the neoplasm was not found. The histopathological examination of samples of brain tissue confirmed the diagnosis of numerous metastases of poorly differentiated carcinoma.
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The patient was a 51-year-old man who was diagnosed as having prostate cancer(adenocarcinoma)in December Year X-3. He underwent total prostatectomy in June Year X-2. The lesions were confined to the right lobe of the prostate.
View Article and Find Full Text PDFFront Vet Sci
February 2025
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States.
Background: Pulmonary involvement of Non-Langerhans Cell Histiocytosis (PNLCH) is a rare cause of interstitial pulmonary disease in people and are classified as either Erdheim-Chester disease (ECD) or Rosai-Dorfman disease (RDD). In veterinary medicine, feline pulmonary Langerhans cell histiocytosis (PLCH) has been identified as an infiltrative histiocytic disorder with an insidious onset of progressive respiratory distress and is non-responsiveness to empiric therapies. Unfortunately, subsequent death either from respiratory failure or humane euthanasia are the reported outcomes in all reported cases.
View Article and Find Full Text PDFClin Neurol Neurosurg
March 2025
Section of Neurosurgery, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan; Center of Oncological Research in Surgery, Aga Khan University Hospital, Karachi, Pakistan. Electronic address:
Introduction: Multicentric and multifocal gliomas are rare and mainly described in high-grade gliomas, however, they have rarely been reported with LGG in about 2-10 % of all cases. This study aims to identify the reported multicentric low-grade gliomas (mLGGs) in literature and review their pathologies, management, and outcomes.
Methods: A systematic search using a pre-defined search strategy was conducted across three databases (PubMed, Cochrane Library, and Scopus).
J Infect Public Health
March 2025
Public Health Laboratory, Biothreat Response Department, Saudi Public Health Authority, Riyadh, Saudi Arabia.
Mycobacterium riyadhense is a newly discovered, slow-growing nontuberculous mycobacterium with an emerging global distribution. We report a case of multifocal osteolytic lesions as the first sign of infection in a previously healthy 39-year-old female. M.
View Article and Find Full Text PDFBMC Med Genomics
March 2025
Department of Urology, The First Hospital of Shanxi Medical University, Taiyuan, China.
Background: Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a rare cause of overt Cushing's syndrome (CS), which usually manifests as bilateral macronodular adrenal nodules and varying levels of cortisol secretion. Previous studies have shown that ARMC5 play a huge role in the occurrence of PBMAH, which may be inherited to family members and lead to more severe clinical symptoms. ARMC5 variants may be associated with meningiomas, which is also illustrated by our report.
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