The inflammatory bowel disease questionnaire: a valid and reliable measure in ulcerative colitis patients in the North East of England.

Scand J Gastroenterol

University of Newcastle Regional School of Medicine, North Tyneside General Hospital, North Shields, Tyne and Wear, UK.

Published: September 1998

Background: The validity and reliability of the Inflammatory Bowel Disease Questionnaire (IBDQ) needed to be confirmed before its use in the UK.

Methods: The IBDQ was administered to 28 subjects with ulcerative colitis (UC) on 3 separate occasions over a period of 4 weeks, twice by an interviewer and once by self-completion. Convergent and concurrent validity was assessed by using the Colitis Activity Index (CAI) and the Short Form 36 Health Survey (SF-36). Test-retest reliability and internal consistency were also tested.

Results: There were moderately high Pearson correlations between related IBDQ domains and SF-36 dimensions and also between the CAI score and the IBDQ Bowel domain and the SF-36 Pain dimension. Cronbach's alpha, corrected item-total correlations, and intra-class correlation coefficients were high.

Conclusions: The IBDQ is a valid and reliable health-related quality of life scale for use in patients with UC and is suitable for use in the UK.

Download full-text PDF

Source
http://dx.doi.org/10.1080/003655298750026994DOI Listing

Publication Analysis

Top Keywords

inflammatory bowel
8
bowel disease
8
disease questionnaire
8
valid reliable
8
ulcerative colitis
8
ibdq
5
questionnaire valid
4
reliable measure
4
measure ulcerative
4
colitis patients
4

Similar Publications

Background: Inflammatory bowel disease (IBD) is a chronic disease that includes Crohn's disease and ulcerative colitis. Studies found that 40-60% of women diagnosed with IBD have sexual dysfunction (SD).

Aims: To determine SD and associated factors in women with IBD.

View Article and Find Full Text PDF

TTC7A Variants Results in Gastrointestinal Defects and Immunodeficiency Syndrome: Case Series and Literature Review.

Clin Rev Allergy Immunol

January 2025

Department of Neonatal Surgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.

Gastrointestinal Defects and Immunodeficiency Syndrome-1 (GIDID-1), caused by abnormalities in TTC7A, is an autosomal recessive disorder characterized by multiple gastrointestinal malformations and immune deficiencies, often accompanied by inflammatory bowel disease (IBD). This condition typically results in poor treatment outcomes and is usually fatal in early infancy. This paper examined the genetic abnormalities and clinical features of GIDID by analyzing data from three children and one fetus with gastrointestinal dysfunction and immune deficiency associated with TTC7A abnormalities at our hospital, and reviewed reported cases worldwide.

View Article and Find Full Text PDF

Curcuminoids, found in turmeric ( L.), include curcumin (CUR), demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC). Although CUR and DMC are well-studied, the anti-inflammatory effects of BDMC remain less explored.

View Article and Find Full Text PDF

Background And Aims: Probe-based confocal endomicroscopy (pCLE) allows real-time microscopic visualization of the intestinal mucosa surface layers. Despite remission achieved through anti-tumor necrosis factor or vedolizumab therapy, anomalies in the intestinal epithelial barrier are observed in inflammatory bowel disease (IBD) patients. Our study aimed to assess these abnormalities in non-IBD individuals and compare them with IBD patients in endoscopic remission to identify the associated factors.

View Article and Find Full Text PDF

Telocytes in inflammatory bowel diseases: contributions to pathology and therapeutic potentials.

Front Cell Dev Biol

January 2025

Division of Gastroenterology and Hepatology, Department of Medicine, Penn State College of Medicine, Hershey, PA, United States.

Telocytes, a novel mesenchymal cell population, are characterized by their distinctive long and slender projections known as telopodes and have garnered significant interest since their formal introduction to the literature in 2010. These cells have been identified in various tissues, including the gastrointestinal (GI) tract, where they are suggested to play important roles in maintaining structural integrity, immune modulation, and barrier function. Inflammatory bowel diseases (IBD), which include Crohn's disease (CD) and ulcerative colitis (UC), are characterized by chronic inflammation and fibrosis.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!