Purpose: Retrospective analysis of results of treatment of 132 subclinical ductal carcinomas in situ, non-palpable.

Material And Methods: Patients were treated with limited surgery and 70 Gy radiation therapy (70 Gy).

Results: With a median follow-up of 7 years, the total recurrence rate was 6%, and the actuarial rate at 5 years 4% and at 10 years 13% at. These have no influence on recurrence on the specific actuarial survival rate which was 100% at 10 years. In spite of five infiltrating recurrences of seven, no metastasis appeared 48 months after the salvage surgery. The global rate of breast preservation was 92% at 7 years.

Discussion And Conclusion: Therapeutic indications were developed taking into account the present analysis and a literature review (2,338 in situ ductal carcinomas, palpable or not, treated with conservative surgery, with or without adjuvant radio-therapy).

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http://dx.doi.org/10.1016/s1278-3218(98)89057-4DOI Listing

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