A common method of choosing the link function in generalized linear models is to specify a parametric link family indexed by unknown parameters. The maximum likelihood estimates of such link parameters, however, may often depend on one or several extreme observations. Diagnostics are derived to assess the sensitivity of the parametric link analysis. Two examples demonstrate that the proposed diagnostics can identify jointly influential observations on the link even when masking is present.
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http://dx.doi.org/10.1080/10543409808835248 | DOI Listing |
Genetics
January 2025
School of BioSciences, The University of Melbourne, Royal Parade, Parkville, VIC 3010, Australia.
Genomic prediction applies to any agro- or ecologically relevant traits, with distinct ontologies and genetic architectures. Selecting the most appropriate model for the distribution of genetic effects and their associated allele frequencies in the training population is crucial. Linear regression models are often preferred for genomic prediction.
View Article and Find Full Text PDFJ Child Adolesc Psychopharmacol
January 2025
Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Autism spectrum disorder (ASD) is characterized by deficits in social behavior and executive function (EF), particularly in cognitive flexibility. Whether transcranial magnetic stimulation (TMS) can improve cognitive outcomes in patients with ASD remains an open question. We examined the acute effects of prefrontal TMS on cortical excitability and fluid cognition in individuals with ASD who underwent TMS for refractory major depression.
View Article and Find Full Text PDFEntropy (Basel)
December 2024
Volgenau School of Engineering, George Mason University, 4400 University Drive, MSN 5D3, Fairfax, VA 22030, USA.
Generative Bayesian Computation (GBC) methods are developed to provide an efficient computational solution for maximum expected utility (MEU). We propose a density-free generative method based on quantiles that naturally calculates expected utility as a marginal of posterior quantiles. Our approach uses a deep quantile neural estimator to directly simulate distributional utilities.
View Article and Find Full Text PDFEur Radiol
December 2024
Guerbet Research, Paris, France.
Objectives: This study aims to evaluate a deep learning pipeline for detecting clinically significant prostate cancer (csPCa), defined as Gleason Grade Group (GGG) ≥ 2, using biparametric MRI (bpMRI) and compare its performance with radiological reading.
Materials And Methods: The training dataset included 4381 bpMRI cases (3800 positive and 581 negative) across three continents, with 80% annotated using PI-RADS and 20% with Gleason Scores. The testing set comprised 328 cases from the PROSTATEx dataset, including 34% positive (GGG ≥ 2) and 66% negative cases.
BMC Infect Dis
December 2024
Department of Epidemiology and Biostatistics, School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.
Introduction: Tuberculosis (TB) remains the most common opportunistic infection and leading cause of death among individuals living with HIV/AIDS in Ethiopia. Its significant impact on morbidity and mortality underscores the crucial link between these two diseases. While the advent of antiretroviral therapy (ART) has led to a dramatic decline in mortality rates among HIV/AIDS patients, TB continues to pose a substantial threat.
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