Base composition distribution of pyrimidine isopliths with general formula PyrnPn+1 in DNA of Actinomyces coelicolor 66 Kras. and in DNK of its actinophage F448 were investigater. These DNAs differ both pyrimidine isoplith distribution and in composition. The quality of shorter pyrimidine tracts in Actinomyces coelicolor DNA is higher compared with that in actinophage F448 DNA. The possibility of exogenic origin of actinophage F448 is discussed.

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