Even though the chorioallantoic placenta of Suncus has been previously investigated with light and electron microscopy, controversies related to its structure still remain. To resolve these, Suncus murinus placentae from several (early and late limb bud, advanced pregnancy, and full term) were examined by electron microscopy. The interhemal membrane of Suncus comprises a maternal endothelium with basal lamina, syncytial trophoblast with its basal lamina, fetal mesenchyme, and fetal capillary endothelium. Layering of these components remain unchanged throughout gestation. The most striking feature of the interhemal membrane is the hypertrophied mesenchymal and maternal epithelial layers. The syncytiotrophoblast develops into a sieve-like transtrophoblastic spongy layer bearing numerous processes of the hypertrophied maternal endothelium. Mesenchymal cells intervene amidst the fetal endothelium displaying a high protein synthesizing activity. The interhemal membrane of Suncus is confirmed to be endotheliochorial.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Methotrexate enhances oxidative stress, apoptosis, and ultrastructural alterations in the placenta of rat.
Ultrastruct Pathol
November 2022
Human Anatomy and Embryology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
The chemotherapeutic drug methotrexate (MTX) is utilized to treat various malignancies. MTX exposure during pregnancy causes miscarriages, abnormalities in newborns, and developmental delays. The current study examined the placenta's sequential histopathological alterations following exposure to the MTX in pregnant rats.
View Article and Find Full Text PDFHyperglycemia results in significant pathophysiological changes of placental spiral artery remodeling and angiogenesis, further contributing to congenital defects.
Front Biosci (Landmark Ed)
November 2021
Department of Nutrition, Texas A&M University, College Station, TX 77843, USA.
: Hyperglycemic conditions achieved during pregnancy have been shown to have detrimental effects to fetal development and increase the prevalence of childhood comorbidities. However, the mechanisms in which diabetic pregnancies affect placental development and subsequently contribute to adverse health effects on the mother and offspring remain unclear. : Streptozotocin was used to induce gestational diabetes in mice.
View Article and Find Full Text PDFQuercetin improved histological structure and upregulated adiponectin and adiponectin receptors in the placenta of rats with gestational diabetes mellitus.
Placenta
March 2021
Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Introduction: Gestational diabetes mellitus (GDM) is a metabolic syndrome among pregnant mothers that increases the risk of developing growth disorders in the fetus and the placenta. Adiponectin is an adipokine, which plays a central role in the regulation of glucose and lipid metabolism, energy homeostasis, and insulin resistance in various tissues. Quercetin is a natural flavonoid with beneficial effects in the diabetic animal model, but data related to its effect on histological change and adiponectin system in the placenta of GDM are limited.
View Article and Find Full Text PDFEffect of aspartame on the placenta of adult albino rat. A histological and immunohistochemical study.
Ann Anat
July 2019
Human Anatomy and Embryology Department, Faculty of Medicine, Zagazig University, Egypt. Electronic address:
Aspartame is an artificial sweetener usually consumed by hundreds of millions of persons all over the world. Its metabolites can be toxic to many organs and there are only a few studies on the use of aspartame during gestation. The present study was designed to fully evaluate the effect of aspartame on the histological structure of the placenta in the adult albino rat.
View Article and Find Full Text PDFPlacentation in watersnakes II: Placental ultrastructure in Nerodia erythrogaster (Colubridae: Natricinae).
J Morphol
May 2017
Department of Biology, Boston University, Boston, Massachusetts, 02215.
Ultrastructure of the placental tissues from redbelly watersnakes (Nerodia erythrogaster) was analyzed during late pregnancy to provide insight into placental development and function. Examination of the chorioallantoic placenta with transmission electron microscopy reveals that chorionic and uterine epithelia are extremely attenuated but intact and that the eggshell membrane is vestigial and lacks a calcareous layer. These features minimize the interhemal diffusion distance across the placenta.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!