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Disulfiram: Mechanisms, Applications, and Challenges.
Antibiotics (Basel)
March 2023
Lyme & Tick-Borne Diseases Research Center, Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, Columbia University, New York, NY 10032, USA.
: Since disulfiram's discovery in the 1940s and its FDA approval for alcohol use disorder, other indications have been investigated. This review describes potential clinical applications, associated risks, and challenges. : For this narrative review, a PubMed search was conducted for articles addressing in vivo studies of disulfiram with an emphasis on drug repurposing for the treatment of human diseases.
View Article and Find Full Text PDFLate and chronic Lyme disease.
Med Clin North Am
March 2002
Divisions of Infectious Disease and BioMolecular Medicine, Lyme Disease Unit, Boston University Medical Center, Boston, Massachusetts, USA.
This article reviews the late and chronic manifestations of Lyme disease. Special attention is given to the chronic manifestations of the disease, detailing its pathogenesis, clinical spectrum, and laboratory criteria for the diagnosis. Based on experimental evidence and experience, approaches to the successful treatment of the late and chronic disease are outlined.
View Article and Find Full Text PDF[Lyme disease--its diagnostic and treatment principles].
Bacteriol Virusol Parazitol Epidemiol
September 1998
Institutul Cantacuzino, Bucureşti.
Lyme disease: recognition, management, and prevention in the primary care setting.
Am J Manag Care
July 1997
Schneider Children's Hospital, New Hyde Park, NY 11040, USA.
Unlabelled: This activity is designed for practitioners who see patients with tick bites, Lyme disease, or suspected Lyme disease in their practice, whether or not the practitioner is in an endemic area for Lyme disease.
Goal: To help primary care practitioners recognize and treat Lyme disease and provide preventive counseling.
Objectives: 1.
Lyme disease: considerations for dentistry.
J Orofac Pain
January 1997
TMD and Orofacial Pain Center, University of Medicine and Dentistry, New Jersey Dental School, Newark, USA.
Although Lyme disease has spread rapidly and it is difficult to diagnose, a review of the dental literature does not reveal many references to this illness. Dental practitioners must be aware of the systemic effects of this often multiorgan disorder. Its clinical manifestations may include facial and dental pain, facial nerve palsy, headache, temporomandibular joint pain, and masticatory muscle pain.
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