AI Article Synopsis
- The study examined the coronary arteries of steelhead trout at various stages of sexual maturity to assess for arteriosclerotic lesions.
- Fish that were actively spawning or mature displayed lesions in about 20% of their arterial sections, mainly characterized by smooth muscle cells proliferating into the artery's lumen.
- In mature fish with a fungal infection, the incidence of these lesions was significantly higher, while lesions were generally consistent across different sizes of coronary arteries, except for very small ones.
Article Abstract
Steelhead trout (Salmo gairdnerii) were taken at three stages of sexual maturity to study their coronary arteries for arteriosclerotic lesions. At least 18 sections from the glutaraldehyde- and osmium-fixed arteries were obtained from each fish. Fish in the middle of the spawning migration and sexually mature fish at the spawning ground had lesions in about 20% of the arterial sections. These consisted of focal proliferations of smooth muscle cells projecting into the lumen through the broken elastic lamina with an intact endothelium around them. Sexually mature fish with patches of fungus on their head and back had twice as high a percentage of arterial sections with lesions as the first two groups of fish. Sexually immature fish were not studied. The lesions occurred approximately equally in all sizes of coronary arteries except for very small arteries. All lesions but one were focal; that lesion involved a third of the intima and the media. The lesions have no elastic lamina below the endothelium and seem to have no lipid.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0021-9150(76)90130-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Freshwater browning as a hidden threat - Transcriptomic responses in fish gills exposed to fulvic acid.
J Hazard Mater
January 2025
Research Institute for Farm Animal Biology, Dummerstorf, Germany.
Human activities and climate change have significantly increased humic substances in freshwater ecosystems over the last few decades. This increase is particularly concerning during seasonal changes or after heavy rainfall, when concentrations can easily increase up to tenfold. This phenomenon, known as "browning," has unknown consequences for aquatic organisms.
View Article and Find Full Text PDFComparative characterization of organ-specific phase I and II biotransformation enzyme kinetics in salmonid S9 sub-cellular fractions and cell lines.
Cell Biol Toxicol
January 2025
Department of Environmental Toxicology, Swiss Federal Institute of Aquatic Science and Technology, Eawag, 8600, Dübendorf, Switzerland.
Advancing in vitro systems to address the effects of chemical pollution requires a thorough characterization of their functionalities, such as their repertoire of biotransformation enzymes. Currently, knowledge regarding the presence, activity magnitudes, and inducibility of different biotransformation pathways in vitro is scarce, particularly across organs. We report organ-specific kinetics for phase I and II biotransformation enzymes, under basal and induced conditions, in two in vitro systems using salmonid fish: S9 sub-cellular fractions from brown trout (Salmo trutta) and rainbow trout (Oncorhynchus mykiss) were compared with rainbow trout cell lines.
View Article and Find Full Text PDFImproved Protective Efficacy in Rainbow Trout (Oncorhynchus mykiss) Against Vibrio anguillarum Through Immunization with a Combination of Formalin-Killed and Auxotrophic-Live V. anguillarum.
Mar Biotechnol (NY)
January 2025
Department of Aquatic Life Medicine, Pukyong National University, Busan, 48513, South Korea.
Vibriosis caused by Vibrio anguillarum has been an important bacterial disease in cultured rainbow trout (Oncorhynchus mykiss). In the present study, we evaluated the protective efficacy of a vaccine that consists of formalin-killed (FK) V. anguillarum and the alr genes knockout auxotrophic-live (AL) V.
View Article and Find Full Text PDFMicroRNA-203-3p participates in antiviral immune response by negatively regulating TRAF3 in the rainbow trout (Oncorhynchus mykiss).
Fish Shellfish Immunol
January 2025
College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, 730070, China.
MicroRNAs (miRNAs) are highly conserved endogenous non-coding RNAs that play a crucial role in fish immune response by regulating gene expression at the post-transcriptional level. In recent years, the viral diseases caused by infectious hematopoietic necrosis virus (IHNV) have caused significant economic losses in rainbow trout (Oncorhynchus mykiss) aquaculture, whereas the immune regulatory mechanisms of miRNAs involved in rainbow trout resistance to IHNV infection remains largely undefined. In this study, we analyzed the structural characteristics of Oncorhynchus mykiss tumor necrosis factor receptor-associated factor 3 (OmTRAF3) by bioinformatics software and explored the molecular mechanism of miR-203-3p in rainbow trout resistance to IHNV by regulating OmTRAF3 in vivo and in vitro.
View Article and Find Full Text PDFEnvironmental exposure to single and combined ZnO and TiO nanoparticles: Implications for rainbow trout gill immune functions and microbiota.
Chemosphere
January 2025
Research Unit in Environmental and Evolutionary Biology (URBE), Institute of Life Earth and Environment, University of Namur, 61 Rue de Bruxelles, B-5000, Namur, Belgium.
ZnO and TiO nanoparticles (NPs) are widely employed for their antibacterial properties, but their potential environmental impact is raising concerns. This study aimed to assess their single and combined effects at environmentally relevant concentrations (210 μg L) on rainbow trout (Oncorhynchus mykiss) gills microbiota and immune functions. 16S rRNA gene sequencing performed after 5 and 28 days of exposure suggests that TiO NPs had a more immediate impact on bacterial diversity, while prolonged exposure to the mixture altered community composition.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!