The diagnosis of breast cancer causes severe psychological conflicts. This is because of the sudden need for a mutilating breast operation and because of the threatening confrontation with a potentially lethal disease. The consequence can be a spectrum of physical and mental sequelae, access to which the physician may find difficult. Here, the interpersonal relationship between the patient and the operating surgeon is of particular relevance, not only for the hospital phase but also in the time to follow. These effects therefore fall into the sector of psychosocial care. Within this framework, an improvement of the postoperative quality of life may be the result, probably via emotional processes. Various recent studies have confirmed the empirical finding that this care may result in an extension of the survival time. The acute psychological care by the operator involves: diagnostic, response to diagnosis, decision making of the patient, informed consent, the perioperative phase, postoperative information and the further "decision making" because of the operative findings, and discussion at the time of discharge. In connection with the informed consent there are several points of a heavy psychological load; namely, the likelihood of the diagnosis, the problem of the intraoperative histology and their consequences, procedure modalities, the possibility of a one-stage- or two-stage-operation, the meaning of the type of incision, the consequences and need for a lymph node excision, information about possible complications, discussion about postoperative treatment modalities, the prognosis and finally of psychological points of view. The influence of the surgeon is in this regard is of great importance. Especially as concerns the alternatives of tumorectomy with radiation and mastectomy (without radiation) and possible reconstruction. Other problems are connected to possible adjuvant chemotherapy or hormone therapy and perhaps bone marrow transplantation. Alternative conservative therapeutic modalities are, also of special interest.
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J Infect Dev Ctries
December 2024
The Cancer Hospital Affiliated to Shandong First Medical University (Shandong Cancer Prevention Research Institute, Shandong Cancer Hospital), Jinan 250117, China.
Introduction: In this study, we analyzed the psychological aspects of coronavirus disease 2019 (COVID-19) patients who were discharged from the hospitals in Shanghai, China, and later had positive nucleic acid retest results for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant infection (re-positive COVID-19). The purpose was to gain clarity on the patients' needs and to provide evidence for the medical staff to deliver scientific and targeted health care to the patients.
Methodology: We screened patients who tested positive for SARS-CoV-2 Omicron variant infection by nucleic acid testing after having previously recovered from a COVID-19 infection and being discharged from Shanghai shelter hospitals or COVID-19-designated hospitals from April 3, 2022, to May 10, 2022.
Transl Psychiatry
January 2025
Department of Genetic Psychology, Faculty of Psychology, Ruhr-University Bochum, Universitätsstraße 150, Bochum, Germany.
Cell-free DNA (cfDNA) is continuously shed by all cells in the body, but the regulation of this process and its physiological functions are still largely unknown. Previous research has demonstrated that both nuclear (cf-nDNA) and mitochondrial (cf-mtDNA) cfDNA levels increase in plasma in response to acute psychosocial and physical stress in males. This study further investigated these findings by testing 31 female participants (16 using oral hormonal contraception and 15 not using oral hormonal contraception), and the results were subsequently compared with those of 16 male participants.
View Article and Find Full Text PDFObjective: To explore the lived experiences and extent of cognitive symptoms in Long COVID (LC) in a UK-based sample.
Design: This study implemented a mixed-methods design. Eight focus groups were conducted to collect qualitative data, and the Framework Analysis was used to reveal the experiences and impact of cognitive symptoms.
HIV Res Clin Pract
December 2025
Division of Infectious Diseases and Global Public Health, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA.
Background: HIV remains a major challenge in KwaZulu-Natal, South Africa, particularly for young women who face disproportionate risks and barriers to prevention and treatment. Most HIV cure trials, however, occur in high-income countries.
Objective: To examine the perspectives of young women diagnosed with acute HIV in a longitudinal study, focusing on their perceptions on ATI-inclusive HIV cure trials and the barriers and facilitators to participation.
J Clin Med
January 2025
Disturbances of Growth and Development on Children Research Center, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), is increasingly recognized as a condition affecting not only adults but also children and adolescents. While children often experience milder acute COVID-19 symptoms compared to adults, some develop persistent physical, psychological, and neurological symptoms lasting for weeks or months after initial infection. The most commonly reported symptoms include debilitating fatigue, respiratory issues, headaches, muscle pain, gastrointestinal disturbances, and cognitive difficulties, which significantly impact daily activities, schooling, and social interactions.
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