AI Article Synopsis
- The peripheral nervous system can help diagnose systemic vasculitis, as shown in a study involving eight patients, primarily middle-aged women.
- Among them, four had polyarteritis nodosa, while others had conditions like systemic lupus erythematosus and specific types of vasculitis.
- All patients received a treatment regimen of methylprednisolone and cyclophosphamide; five improved, two showed no change, and one patient died, with improvements typically noted after the third or fourth treatment pulse.
Article Abstract
The peripheral nervous system is frequently involved in systemic vasculitis and it may be helpful in the disease diagnosis. We report on eight patients: seven women and one man; five white, two black and one yellow; age mean 55.9 years; four had polyarteritis nodosa, one had systemic lupus erythematosus, one had isolated peripheral nerve vasculitis and one had livedoid vasculitis. All of them received endovenous therapy with "pulse" of methylprednisolone (1 g/day/3 days) and cyclophosphamide (1 g/1 day). Five patients improved, two remained unchanged and one died. The neurological improvement occurred after the third or fourth pulse and in the patients who have had a shorter time of disease.
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| http://dx.doi.org/10.1590/s0004-282x1998000200018 | DOI Listing |
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