500 melanocytic lesions were examined by dermatoscopy using the ABCD rule prior to excision and histologic diagnosis. Regular nevi (n = 272) exhibited a score of 3.55 +/- 0.87, nevi with histologic signs of dysplasia (n = 190) a score of 4.0 +/- 0.68 and melanomas (n = 30) a score of 5.08 +/- 1.24. This study suggests that the ABCD rule of dermatoscopy greatly facilitates the evaluation of melanocytic lesions. When the dermatoscopic score is higher than 4.2, melanoma should be considered.
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http://dx.doi.org/10.1007/s001050050772 | DOI Listing |
Acute diarrheal disease is one of the leading causes of death in children under age 5, disproportionately impacting children in low-resource settings. Many of these cases are caused by bacteria and therefore could respond to antibiotic treatment; however, the benefits of widely prescribing antibiotics must be weighed against the risks for the emergence of microbial resistance. These challenges present the opportunity for developing individualized treatment guidelines for diarrheal disease.
View Article and Find Full Text PDFNeurosci Bull
January 2025
State Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, 100875, China.
Attention deficit hyperactivity disorder (ADHD), a prevalent neurodevelopmental disorder influenced by both genetic and environmental factors, remains poorly understood regarding how its polygenic risk score (PRS) impacts functional networks and symptomology. This study capitalized on data from 11,430 children in the Adolescent Brain Cognitive Development study to explore the interplay between PRS, brain function, and behavioral problems, along with their interactive effects. The results showed that children with a higher PRS exhibited more severe attention deficits and rule-breaking problems, and experienced sleep disturbances, particularly in initiating and maintaining sleep.
View Article and Find Full Text PDFJ Environ Manage
December 2024
Civil Engineering Department, Engineering Faculty, Firat University, 23119, Elazig, Turkey; SEBIZA Technology Limited Company, Firat Technopark, 23350, Elazig, Turkey.
This study focuses on modelling sustainable concretes' mechanical and environmental properties with interpretable artificial intelligence-based automated rule extraction, management of waste materials, and meeting future prospects. In this context, 24 sustainable concrete series containing fly ash and recycled aggregates were produced. Compressive strength tests were performed on these specimens at 7, 28, and 90 days, and their mechanical properties were evaluated.
View Article and Find Full Text PDFSci Rep
November 2024
FMPR, Mohammed V University in Rabat, Rabat, Morocco.
This research introduces a Computer-Aided Diagnosis-system designed aimed at automated detections & classification of tomato leaf diseases, combining traditional handcrafted features with advanced deep learning techniques. The system's process encompasses preprocessing, feature extraction, feature fusion, and classification. It utilizes enhancement filters and segmentation algorithms to isolate with Regions-of-Interests (ROI) in images tomato leaves.
View Article and Find Full Text PDFJ Clin Aesthet Dermatol
January 2024
Dr. Harrison is with Forefront Dermatology in Englewood, Colorado, and is a Diplomat Fellow of the SDPA; she was with the Doctor of Medical Science Program, AT Still University in Mesa, Arizona at the time of writing.
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