AI Article Synopsis
- Novel endothelin antagonists (nahocols A, A1, B, C, D1, D2, and isonahocols D1, D2) were discovered in the brown alga Sargassum autumnale.
- Their structural characteristics were identified using NMR spectroscopy and various chemical reactions.
- Nahocols feature an aryl prenyl ether structure, possibly serving as biogenetic precursors for other prenyl compounds found across different species in the plant and animal kingdoms.
Article Abstract
Novel endothelin antagonists, nahocols A, A1, B, C, D1 and D2, and isonahocols D1 and D2, were isolated from the brown alga, Sargassum autumnale. Their structures were determined through detailed analysis of NMR spectra and chemical reactions. Nahocols have an aryl prenyl ether structure, which are speculated to be biogenetic precursors of the ubiquitous prenyl hydroquinones or prenyl benzoquinones in the plant and animal kingdoms.
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| http://dx.doi.org/10.1016/s0031-9422(97)00476-7 | DOI Listing |
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