As many as 120 neonates and their mothers presenting with persistency of cytomegaly virus were studied for impact of maternal specific antibodies to cytomegaly virus on rhe pattern of clinical adaptation in children. 90% of children born of infected mothers display neurologic disturbances, 71.4% have jaundice accompanied by hyperbilirubinemia, 4.7% present with hemorrhagic syndrome. 11 neonates were diagnosed as having cytomegaloviral infection, four such diagnoses were made in a pathoanatomical setting. Thus, the studies made suggest that cytomegaly virus might be neurotrophic and that maternal specific antibodies have negative impact on postnatal adaptation of neonates.
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