Changes in the plasma transcortin level were studied in patients with primary glaucoma, glaucoma and diabetes, diabetes mellitus compared with a control croup. It was found that the plasma transcortin level of the patients with or without glaucoma was significantly higher than that of the control values. Moreover, the analysis of the dissociation constant of transcortincorticosterone complex revealed that it is greater in patients with primary glaucoma than could be expected by the dilution ratio. Further studies are required to understand the mechanism of the changes occurring in plasma transcortin level in glaucoma.

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