In 25 eyes suffering from primary open angle glaucoma the facility of outflow was measured before and 1 to 3 months after surgery in consideration of the rigidity. Trabeculotomy improved the facility on an average of 0.14+/-0.02 to 0.28+/-0.03 units. This means that the outflow resistance is decreased from 10.58+/-1.34 to 4.31+/-0.45 units. The statistically highly significant improvement of the outflow conditions must be a consequence of the surgical opening in the trabecular meshwork as the sclera had been closed watertightly at the end of the trabeculotomy. The coefficient of rigidity (graphically determined by applanation tonometry and Schiötz tonometry in recumbent position) was decreased from 0.0208+/-0.0010 to 0.0172+/-0.0008. This means that measuring the intraocular pressure postoperatively with a Schiötz tonometer results in data which are 3.08+/-0.65 mm Hg lower than the actual pressure level.
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Br J Ophthalmol
October 2020
Ophthalmology, King's College London, London, UK
Background: The determinants of success of selective laser trabeculoplasty (SLT) in treatment-naïve patients with open angle glaucoma (OAG) and ocular hypertension (OHT) have not been understood fully. Therefore, we have conducted this study to explore the predictors of success.
Methods: This is a retrospective review of a pre-existing database of patients who had received primary SLT at St Thomas' Hospital, London, UK.
Invest Ophthalmol Vis Sci
March 2017
Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska, United States 2Case Western Reserve University, Cleveland, Ohio, United States.
Purpose: This study was designed to evaluate the changes in aqueous humor dynamics (AHD) produced by selective laser trabeculoplasty (SLT) and to explore if baseline AHD parameters are predictive of IOP response to SLT.
Methods: Thirty-one consecutive subjects diagnosed with ocular hypertension or primary open-angle glaucoma scheduled to undergo SLT as their primary IOP-lowering therapy were enrolled in this prospective observational study. Subjects underwent baseline assessment of AHD in both eyes.
J Glaucoma
December 2013
Department of Ophthalmology, St Thomas' Hospital, London, UK.
Br J Ophthalmol
November 2010
Department of Ophthalmology, St Thomas' Hospital, London, UK.
Purpose: To investigate the effect of 180° versus 360° primary selective laser trabeculoplasty (SLT) on tonographic outflow facility and intraocular pressure (IOP).
Design: Prospective, single masked randomised clinical trial.
Participants: Patients with untreated primary open angle glaucoma or ocular hypertension both with IOP > 21-35 mmHg.
J Am Vet Med Assoc
December 1987
Department of Comparative Ophthalmology, College of Veterinary Medicine, University of Florida, Gainesville 32610-0125.
The Krupin-Denver valve was implanted unilaterally in 2 normotensive and in 6 glaucomatous Beagles. The fellow eye of each dog had an external trabeculectomy. Before and after surgery, all dogs were evaluated serially by gonioscopy, biomicroscopy, tonometry, and tonography.
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