We report here the 1244-bp sequence of a Streptococcus pneumoniae chromosomal fragment that contains the putative promoter and protein-coding region of the lactate dehydrogenase gene (ldh). The nucleotide sequence predicts a protein of 327 aa with a molecular weight of 35,202 daltons, after removal of the N-terminal methionine residue. The ldh gene is located on the ApaI fragment 1 and SmaI fragment 2 of the previously reported physical map of S. pneumoniae chromosome.
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http://dx.doi.org/10.1007/s002849900342 | DOI Listing |
Chembiochem
January 2025
Ludwig-Maximilians-Universitat Munchen, Chemistry, Butenandstr. 5-13, 81377, Muenchen, GERMANY.
In the last decade the important role of small non-coding RNAs such as micro RNAs (miRs) in gene regulation in healthy and disease states became more and more evident. The miR-200-family of miRs has been shown to play a critical role in many diseases such as cancer and neurodegenerative disorders and could be potentially important for diagnosis and treatment. However, the size of miRs of about ~21-23nt provide challenges for their investigation.
View Article and Find Full Text PDFJ Oral Biol Craniofac Res
December 2024
Department of Orthodontics, University of Washington, Seattle, USA.
Objective: To evaluate the pharyngeal airway dimensions and regional pharyngeal adipose distribution in the young adult minipig model.
Materials And Methods: Eight 7-8-months-old Yucatan minipigs, half male and female, were sedated and placed prone to scan the pharyngeal region. Magnetic resonance imaging (MRI) was performed using dynamic turbo-field echo (TFE)-sequence with respiratory gating and adipose-weighted sequence.
HLA
January 2025
Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Medical University, Moscow, Russia.
The new HLA-C*12:02:55 allele showed one synonymous nucleotide difference compared to the HLA-С*12:02:02:01 allele in codon 134.
View Article and Find Full Text PDFHLA
January 2025
Federal State Budget Institution National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, Moscow, Russia.
The new HLA-B*35:01:80 allele showed one synonymous nucleotide difference compared to the HLA-B*35:01:01:01 allele in codon 137.
View Article and Find Full Text PDFPhysiol Plant
January 2025
College of Horticulture, Hunan Agricultural University, Changsha, China.
Sulforaphane (SF) is a sulfur (S)-containing isothiocyanate found in cruciferous vegetables and is known for its potent anticancer properties. Broccoli sprouts, in particular, are considered safe and healthy dietary choices due to their high SF content and other beneficial biological activities, such as enhanced metabolite ingestion. The application of selenium (Se) is an excellent approach to enhance the abundance of SF.
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