Thallium-201, 129Cs, 43K, and 81Rb were evaluated as "static" myocardial-imaging agents. Optimal settings of the scintillation camera were determined for each agent. Accumulation for good-quality images can be started as early as 5 min after the dose with 43K, 10 min with 201T1, and 30 min with 129Cs. Imaging times were comparable for 43K, 129Cs, and 201T1 (using the 80-keV x-rays). High-energy photons from the 81Rb preparation, largely from 82mRb contaminant, made it impossible to obtain an interpretable image without the addition of more shielding. Absorbed radiation dose from 81Rb is lower than that from 43K, 129Cs, and 201T1. The highest background activity was observed with 81Rb, followed by 43K, 129Cs, and 201T1 in that order. Overall, 201T1 was best suited for imaging acute myocardial infarction with currently available equipment, and 129Cs was next best. However, because of instrument setting and commercially obtained preparations, 81Rb could not be properly compared with the other radionuclides in our study.
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Thallium-201, 129Cs, 43K, and 81Rb were evaluated as "static" myocardial-imaging agents. Optimal settings of the scintillation camera were determined for each agent. Accumulation for good-quality images can be started as early as 5 min after the dose with 43K, 10 min with 201T1, and 30 min with 129Cs.
View Article and Find Full Text PDFLine-source response functions and modulation transfer functions (MTFs) were used to compare the resolution obtained with four myocardial-imaging agents: 129Cs, 43K, 13N-ammonia, and 81Rb contamination. When an Anger camera with pinhole collimator was used, the order of decreasing resolution was 129Cs, 43K, 13N, and 81Rb. Two techniques were employed to determine the extent to which spatial resolution could be improved.
View Article and Find Full Text PDFDosimetry of four heart-imaging radionuclides: 43K, 81Rb, 129Cs, and 201Ti.
J Nucl Med
November 1975
In conjunction with research into the relative clinical suitability of radionuclides for heart imaging, estimates of the radiation dosimetry for 43K, 81Rb, 129Cs, and 201Tl were calculated. Estimates of absorbed radiation dose for the heart, kidneys, liver, lungs, testes, and whole body of the standard man were computed from published distribution data in rats via the MIRD method by assuming that the concentration in each organ per initial mean whole-body concentration is the same in rats and humans. The whole-body absorbed radiation doses from 81Rb, 129Cs, 201Tl, and 43K are 0.
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