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Neuroparacoccidioidomycosis.
J Assoc Physicians India
June 2024
Director ICU, Department of Intensive Care Unit, Ruby Hall Clinic, Pune, Maharashtra, India.
Paracoccidioidomycosis (PCM) is caused by a dimorphic fungus Paracoccidioides Brasiliensis and is endemic to subtropical areas of Central and South America. CNS involvement of PCM is extremely variable. NeuroPCM is found in 9.
View Article and Find Full Text PDFSynovial Fluid in Knee Osteoarthritis Extends Proinflammatory Niche for Macrophage Polarization.
Cells
December 2022
Department of Pathophysiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411 Tartu, Estonia.
Macrophage polarization is a steering factor of osteoarthritis (OA) progression. Synovial fluid (SF) obtained from OA patients with different Kellgren-Lawrence grades (KL grades) holds several proinflammatory factors and was hypothesized to induce macrophage differentiation and polarization by providing the needed microenvironment. U937 cells and peripheral-blood-mononuclear-cell-derived monocytes (PBMC-derived CD14+ cells) were induced with SFs of progressive KL grades for 48 h, and the status of the differentiated cells was evaluated by cell surface markers representing M1 and M2 macrophage phenotypes.
View Article and Find Full Text PDFA rare case of woolly hair with unusual associations.
Indian Dermatol Online J
July 2013
Department of Dermatology, Command Hospital (Southern Command), Wanowrie, Pune, Maharashtra, India.
Woolly hair is a congenital abnormality of scalp hair manifesting as short, kinked hair, which may also involve the hair over the other parts of the body. Keratosis pilaris has been a well known association of woolly hair, and can also be a part of the Naxos or Carvajal syndromes. We herein present a case of woolly hair with associated keratosis pilaris, canaliform dystrophy of nails, increased interdental spaces and recurrent bullous impetigo.
View Article and Find Full Text PDFNecrotizing streptococcal myositis.
ANZ J Surg
April 2009
Department of Surgery, Armed Forces Medical College, Wanowrie, Pune, Maharashtra, India.
Wanowrie virus (WAN) is an ungrouped arbovirus having morphogenetic characters in common with Bunyavirus. It was isolated for the first time from ticks, Hyalomma marginatum isacci (6700 strain) and subsequently from a human case (68923 strain). In the absence of any reports on the prevalence of this virus amongst humans in India, 600 human sera were tested in the Complement Fixation (CF) test against both the strains of WAN virus.
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