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Haemodynamic management of septic shock.
Burns Trauma
January 2025
Australian and New Zealand Intensive Care-Research Centre, Monash University School of Public Health and Preventive Medicine, 553 St Kilda Road, Melbourne VIC 3004, Australia.
Septic shock is a significant challenge in the management of patients with burns and traumatic injuries when complicated by infection, necessitating prompt and effective haemodynamic support. This review provides a comprehensive overview of current strategies for vasopressor and fluid management in septic shock, with the aim to optimize patient outcomes. With regard to vasopressor management, we elaborate on the pharmacologic profiles and clinical applications of catecholamines, vasopressin derivatives, angiotensin II, and other vasoactive agents.
View Article and Find Full Text PDFInterlaboratory assays from the fungal PCR Initiative and the Modimucor Study Group to improve qPCR detection of Mucorales DNA in serum: one more step toward standardization.
J Clin Microbiol
December 2024
Chrono-environnement UMR6249, CNRS, University of Franche-Comté, Besançon, Bourgogne-Franche-Comté, France.
Article Synopsis
- The study aimed to standardize qPCR procedures for diagnosing Mucorales by examining factors that influence DNA extraction and PCR amplification efficiency.
- Two panels of samples were distributed to 26 laboratories, and results showed that using larger serum volumes for DNA extraction and larger input volumes for PCR significantly improved detection sensitivity.
- Findings highlight the importance of optimizing laboratory techniques to enhance diagnosis of Mucormycosis, a serious fungal infection, which is critical for timely treatment in vulnerable patients.
Electrochemical stability of electrospun silicon/carbon nanofiber anode materials: a review.
Phys Chem Chem Phys
January 2025
School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
Silicon (Si) is regarded as a promising anode material owing to its high specific capacity and low lithiation potential. The large volume change and the pulverization of silicon during the lithiation/delithiation process hinder its direct energy storage application. This review focuses on the electrospun silicon/carbon (Si/C) nanofiber anode materials for lithium-ion batteries for long-term stable energy storage.
View Article and Find Full Text PDF[Decolonization of autologous blood with cefuroxime during hardware reinfusion in neurosurgical patients].
Zh Vopr Neirokhir Im N N Burdenko
December 2024
Burdenko Neurosurgical Center, Moscow, Russia.
Article Synopsis
- Autologous blood obtained during surgical hardware reinfusion is often contaminated with bacteria, predominantly from skin microflora, in up to 90% of cases, posing a risk for infection.
- Adding cefuroxime to the blood collection process was found to eliminate bacterial growth in 100% of instances when administered initially.
- Despite various decontamination methods, including washing and leukocyte filtration, some bacterial contamination remained, though the combination of these techniques with cefuroxime significantly reduced the risk of bacterial presence in processed blood samples.
Comparing 1-L and 2-L Polyethylene Glycol with Ascorbic Acid for Small Bowel Capsule Endoscopy: A Randomized Controlled Trial.
Gut Liver
January 2025
Institute for Liver and Digestive Diseases, Hallym University, Chuncheon, Korea.
Background/aims: Small bowel capsule endoscopy (SBCE) has become the standard for initial evaluation in the diagnosis of small bowel lesions. Although optimal visualization of the mucosa is important, patients experience difficulty in consuming a large volume of bowel preparation agents. This study aimed to compare the efficacy and safety of 1-L polyethylene glycol (PEG) with ascorbic acid (AA) and 2-L PEG with AA.
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