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Effect of mild sedation and analgesia on radial artery cannulation in novice residents: a prospective, randomized controlled trial.

BMC Med Educ

December 2024

Department of Anesthesiology and Pain Medicine, the Affiliated Hospital of Jiaxing University, No.1882, South of the Second Ring Road, Jiaxing City, Zhejiang Province, 314000, China.

Background: Radial artery cannulation can be challenging, particularly for inexperienced providers. This study aimed to compare the success rates of resident physicians performing radial artery cannulation with mild sedation and analgesia versus without.

Materials And Methods: This study was a prospective, single-center, double-blind randomized controlled trial.

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Background: Studies suggest that the components of brain-evoked potentials (EPs) may serve as biomarkers of the post-traumatic stress disorder (PTSD) caused by participation in combat operations; however, to date, research remains fragmented, with no studies that have attempted to combine different paradigms. In addition, the mismatch negativity component has not been studied in a Russian sample of veterans with PTSD.

Aim: To identify objective neurophysiological markers of combat-related PTSD using the method of auditory-evoked potentials in active and passive listening paradigms.

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Backgound: Inflammatory hematological ratios (IHRs), such as neutrophil to lymphocyte, monocyte to lymphocyte, and platelet to lymphocyte ratios, are associated with mental disorders, symptoms severity, and the disease phase. Evidence from the studies in adult patients has been summarized in systematic reviews and meta-analyses. The results of the studies in adolescents remain poorly systematized.

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A set of guidelines has been developed to help improve reporting of clinical trials of biofield therapies. The need for enhanced transparency when reporting trials of this family of integrative health practices, e.g.

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