Background: Introducing accreditation as conducted by the Joint Commission on Accreditation of Healthcare Organizations (Oakbrook Terrace, III) into Spain has raised many issues regarding the internationalization of accreditation.
Characteristics Of Accreditation: In recent years more and more countries have considered accreditation a useful tool for the improvement of health care quality. In spite of the differences in the health care systems of the countries where accreditation has been introduced, many of the original characteristics of accreditation as seen in the United States largely remain: peer review evaluation, support of professional associations, voluntary participation, and a national approach. These similarities reflect the fact that the majority of the programs are based on models created by the Joint Commission.
The Experience Of The Avedis Donabedian Foundation: In 1994 the Avedis Donabedian Foundation (FAD), a nonprofit organization founded in Barcelona in 1988, broadened its scope to include accreditation. Having rejected the idea of creating de novo its own standards and accreditation program, FAD worked out an agreement with the Joint Commission whereby FAD would become a Spanish accrediting body to accredit Spanish hospitals but would collaborate with Joint Commission International to adopt the Joint Commission's accreditation standards and processes.
Discussion: The development of accreditation continues. As of spring 1998, seven hospitals and two ambulatory care centers are preparing for accreditation. FAD's experience with adapting the Joint Commission model of accreditation should be instructive to other countries considering health care accreditation.
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http://dx.doi.org/10.1016/s1070-3241(16)30376-5 | DOI Listing |
J Neurochem
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Institute of Biostructures and Bioimaging, Italian National Council for Research (IBB-CNR), Naples, Italy.
The natural compound orotic acid and its anionic form, orotate, play a pivotal role in various biological processes, serving as essential intermediates in pyrimidine de novo synthesis, with demonstrated connections to dietary, supplement, and neurodrug applications. A novel perspective on biomolecular aggregation at the nanoscale, particularly pertinent to neurodegeneration, challenges the established paradigm positing that peptide (amyloid beta) and protein (tau) aggregation mainly govern the molecular events underlying prevalent neuropathologies. Emerging biological evidence indicates a notable role for G-quadruplex (G4) DNA aggregation in neurodegenerative processes affecting neuronal cells, particularly in the presence of extended (GC) repeats in nuclear DNA sequences.
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National Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Provincial Medical Key Laboratory, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China.
Aedes albopictus (Ae. albopictus) is widely distributed and can transmit many infectious diseases, and insecticide-based interventions play an important role in vector control. However, increased insecticide resistance has become a severe public health problem, and the clarification of its detailed mechanism is a matter of urgence.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Microbiology, Genetics, & Immunology, Michigan State University, East Lansing, MI, USA.
In holometabolous insects, critical weight (CW) attainment triggers pupation and metamorphosis, but its mechanism remains unclear in non-model organisms like mosquitoes. Here, we investigate the role of 20-hydroxyecdysone (20E) in CW assessment and pupation timing in Aedes albopictus and Ae. aegypti, vectors of arboviruses including dengue and Zika.
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In vitro toxicology and biomedicine, inaugurated by the Doerenkamp-Zbinden foundation, University of Konstanz, Konstanz, Germany.
On occasion of the DNT5 meeting in Konstanz, Germany (April-2024), participants brainstormed on future challenges concerning a regulatory implementation of the developmental neurotoxicity (DNT) in vitro test battery (DNT-IVB). The five discussion topics below outline some of the key issues, opportunities and research directions for the next several years: (1) How to contextualize DNT hazard with information on potential maternal toxicity or other toxicity domains (non-DNT)? Several approaches on how to use cytotoxicity data from NAMs were discussed. (2) What opportunities exist for an immediate or near-future application of the DNT-IVB, e.
View Article and Find Full Text PDFGlob Chang Biol
January 2025
Departament de Ciències Ambientals, Facultat de Ciències, Universitat de Girona, Girona, Spain.
Biological invasions are a major threat to biodiversity, ecosystem functioning and nature's contributions to people worldwide. However, the effectiveness of invasive alien species (IAS) management measures and the progress toward achieving biodiversity targets remain uncertain due to limited and nonuniform data availability. Management success is usually assessed at a local level and documented in technical reports, often written in languages other than English, which makes such data notoriously difficult to collect at large geographic scales.
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