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Drug Development.
Alzheimers Dement
December 2024
Brigham and Women's Hospital and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
The most recent Alzheimer's clinical trials, including those which reported successful outcomes, use neuroimaging biomarkers of both amyloid and tau for screening participants and demonstrating a treatment effect on pathology. Some of these trials, notably Lecanemab, hint at a potential sex bias in treatment outcome, alluding to major implications for clinical practice when recommending treatment options. Sex differences in treatment response are not surprising given that women are at greater risk of progression to AD dementia, particularly if they carry APOEe4.
View Article and Find Full Text PDFDementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
Chungnam National University, College of Nursing, Daejeon, Korea, Republic of (South).
Background: Older adults in rural areas often face the challenge of managing their health decisions due to limited access to medical services. Cognitive function, particularly the awareness and assessment of one's memory abilities, plays a significant role in the decision-making process. This study investigates the relationship between subjective memory ability and health-related decision-making among older adults in rural areas.
View Article and Find Full Text PDFDementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
Brooklyn College of the City University of New York, Brooklyn, NY, USA.
Background: With the worldwide geriatric population steadily increasing, identifying older adults in need of treatment for cognitive difficulties is imperative. Limited specialty resources makes it particularly important to identify which individuals would most benefit from further evaluation and treatment, including in countries where dementia care is limited, such as India. Self-report measures are timely and cost effective tools that can assist providers in identifying individuals at risk of cognitive decline.
View Article and Find Full Text PDFDementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
IPSIBAT (CONICET/National University of Mar del Plata), Mar del Plata, Buenos Aires, Argentina.
Background: The use of technology in elderly population has increased in the past years due to COVID-19. Therefore it is relevant to identify the factors that contribute and limit the effective use of technology by older people. In particular, digital skills have shown to be relevant to determine the attitude toward the use of technology and consequently to have an effect on usage behavior.
View Article and Find Full Text PDFDementia Care Practice.
Alzheimers Dement
December 2024
Yale School of Public Health, New Haven, CT, USA.
Background: The Republic of Armenia is a post-Soviet, low- and middle-income country (LMIC) in the south Caucasus region with a steadily increasing aging population. The goal of this study was to provide the first look into the national cognitive health in Armenia, considering the growing burden of cognitive impairment (CI) and widespread lack of public awareness about dementia. As a component of the early detection memory screening program launched by Alzheimer's Care Armenia's Brain Health Project and funded through Davos Alzheimer's Collaborative (DAC), this study aimed to understand the prevalence of CI and associated factors across the adult population.
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