AI Article Synopsis
- This study analyzed 13 eyes from 9 patients with intraocular lymphoma over 15 years, noting that inflammation in the front of the eye was generally mild or absent.
- Unlike previous beliefs that this condition mimics uveitis, fundus images showed tumor-like lesions indicating the presence of tumor cell growth rather than just inflammation.
- The study highlights the need for early diagnosis and treatment due to the poor prognosis for patients and the disease's responsiveness to radiation therapy.
Article Abstract
We reviewed a series of 13 eyes in 9 cases of intraocular lymphoma with or without intracranial involvement during the past 15 years. The cases were characterized by moderate or no inflammation in the anterior ocular segment and by the presence of vitreous opacity and fundus lesions. Contrary to the accepted view that this disease simulates uveitis with various manifestations, the fundus lesions in the present series showed disseminated or tumorous subretinal lesions suggestive of proliferation of tumor cells. Only a few cases showed retinal vasculitis or retinal exudates. Electrooculograms showed findings suggestive of widespread impairment of the retinal pigment epithelium. Because of poor prognosis and sensitivity to radiation, we advocate early diagnosis and treatment for this disease.
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