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Synephrine Inhibits Oxidative Stress and HO-Induced Premature Senescence.
Cell Biochem Biophys
January 2025
Department of Maxillofacial Radiology, Field of Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, 890-8544, Japan.
Synephrine, a protoalkaloid found in Citrus aurantium (CA) peels, exerts lipolytic, anti-inflammatory, and vasoconstrictive effects; however, its antioxidant activity remains unclear. In this study, electron spin resonance spectroscopy revealed that synephrine scavenged both hydroxyl and superoxide anion radicals. Several external stimuli, such as HO, X-rays, and ultraviolet (UV) radiation, cause stress-induced premature senescence (SIPS).
View Article and Find Full Text PDFEpidemiology of loneliness & social isolation, an emerging public mental health predicament in India: a scoping review.
Discov Ment Health
January 2025
School of Allied Health Sciences, VIMS Hospital Campus, Vinayaka Mission's Research Foundation - Deemed to be University, Salem, Tamil Nadu, India.
Loneliness and Social Isolation (SI) has evolved into an epidemic and WHO has alarmed many developed and developing countries that their citizens are going through the epidemic of loneliness and SI. It affects the Mental Health status of a person & leads to morbidities and premature death. Loneliness and SI are overlooked subjects resulting in poor research turnover.
View Article and Find Full Text PDFThe interplay of senescence and MMPs in myocardial infarction: implications for cardiac aging and therapeutics.
Biogerontology
January 2025
Centre for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Aging is associated with a marked increase in cardiovascular diseases, such as myocardial infarction (MI). Cellular senescence is also a crucial factor in the development of age-related MI. Matrix metalloproteinases (MMPs) interaction with cellular senescence is a critical determinant of MI development and outcomes, most notably in the aged heart.
View Article and Find Full Text PDFModel Building with Youth: Applying a System Science Approach to Examine the Dynamic Social Context of Adolescent and Young Adult Marijuana Use.
Prev Sci
January 2025
Department of Health Policy and Management, University of North Carolina Chapel Hill Gillings School of Global Public Health, Chapel Hill, NC, USA.
Marijuana use in adolescence is associated with significant adverse outcomes. Romantic relationships are an important context for marijuana use. Prior research suggests a bi-directional relationship between marijuana use and relationship functioning; however, the complex interplay between adolescent relationship dynamics and marijuana use remains unclear.
View Article and Find Full Text PDFPotential Degradation of Low- and High-Density Polyethylene Films by Ochrobactrum intermedium SA1 from Sewage Sludge.
Bull Environ Contam Toxicol
January 2025
Department of Microbiology, Faculty of Allied Health Sciences, Shree Guru Gobind Singh Tricentenary (SGT) University, Gurugram, Haryana, 122505, India.
Accumulation of plastic waste is an alarming environmental concern across globe. For which, microbial degradation offers an efficient ecofriendly solution. Thus, the present study focuses on the exploration of new bacterium that can grow on and utilize polyethylene.
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