Purpose: We evaluated the signal changes of avascular necrosis and transient bone marrow oedema before and after core decompression of the femoral head to deduce prognostic factors for this operative procedure.
Method: 38 to 40 cases with core decompression (35 patients, medium age 44 years) were analysed with a mean follow-up time of 26 months. Preoperatively patients were staged by the ARCO classification. MR-images were judged in accordance to the criteria of Mitchell and Steinberg. The clinical outcome was analysed according to the hip index of Merle D'Aubigne.
Results: All hips with transient bone marrow oedema showed normal signal patterns at an average of 3 months after core decompression. In stage I and II, all patients with a preoperative necrosis area less than 30% of the femoral head showed a reduction of the necrotic zone and good clinical results. An unchanged or progressive appearance was observed in necrotic lesions with more than 30% head involvement. Because of failure a renewed operation had to be done in all patients with stage III and IV.
Conclusion: In the case of transient bone marrow oedema, a restitutio ad integrum can be achieved with core decompression. In stage I and II of avascular necrosis, the successful outcome depends on the lesion size of the femoral head. Necrotic lesions less than 30% seem to have the best prognosis. In stage III and IV, core decompression cannot be recommended.
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http://dx.doi.org/10.1055/s-2008-1051296 | DOI Listing |
J Pediatr Orthop
March 2025
Department of Orthopaedic Surgery, Stanford University, Redwood.
Objective: Steroid-associated osteonecrosis in pediatric patients with inflammatory and oncologic disease is an uncommon yet debilitating condition causing significant functional disability. Pediatric orthopaedic surgeons encounter this population during stages in which surgical intervention may be necessary for joint preservation. Various risk factors for steroid-associated osteonecrosis have been suggested, but a comprehensive systematic review of the literature has not been performed.
View Article and Find Full Text PDFArthrosc Tech
February 2025
Steadman Philippon Research Institute, Vail, Colorado, U.S.A.
Avascular necrosis of the femoral head arises due to inadequate blood supply to the femoral head, leading to cell death, fracture, and eventually collapse. The disease often begins as asymptomatic but can present with pain, stiffness, and limited range of motion in later phases. These symptoms cause disability, predominantly in young to middle-aged individuals.
View Article and Find Full Text PDFBioinformatics
March 2025
Institute of Applied Computer Science, Lodz University of Technology, Lodz, 90-924, Poland.
Summary: The FASTQ format remains at the heart of high-throughput sequencing. Despite advances in specialized FASTQ compressors, they are still imperfect in terms of practical performance tradeoffs. We present a multi-threaded version of Pseudogenome-based Read Compressor (PgRC), an in-memory algorithm for compressing the DNA stream, based on the idea of approximating the shortest common superstring over high-quality reads.
View Article and Find Full Text PDFJ Orthop Surg Res
March 2025
Orthopaedics and Rehabilitation, Yale School of Medicine, Yale University, New Haven, CT, USA.
Background: Osteonecrosis of the femoral head can be a debilitating disease leading to collapse of the femoral head and the subsequent need for a hip arthroplasty. Core decompression has emerged as a leading treatment to prevent collapse. Adjunctive therapies, such as bone graft, bone marrow aspirate concentrates, or synthetic bone substitutes are utilized to promote native bone regeneration.
View Article and Find Full Text PDFCureus
January 2025
Orthopaedics, Unidade Local de Saúde da Póvoa de Varzim/Vila do Conde, Póvoa de Varzim, PRT.
Introduction: Avascular necrosis (AVN) of the femoral head is a complex and debilitating condition that predominantly affects a relatively young population. Core decompression of the femoral head is the primary surgical option for joint preservation, most commonly used in the early stages. However, clinical and radiological outcomes are variable in the literature.
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