AI Article Synopsis
- Desquamative interstitial pneumonia (PID) is a rare lung disorder first described in 1965, characterized by minimal interstitial fibrosis and an accumulation of macrophages in the alveoli.
- Long-term use of Nitrofurantoin has been identified as one of the potential causes of PID, among other aetiologies.
- A case study of a 57-year-old male cigarette smoker diagnosed with PID through lung biopsy highlights the condition's pathogenesis and various possible causes.
Article Abstract
Desquamative interstitial pneumonia (PID) is a rare disorder initially described by Liebow in 1965. It is characterised by the presence of an interstitial pneumonia consisting of minimal lesions of interstitial fibrosis and by the accumulation of a rich intraalveolar cellular material principally composed of macrophages. Numerous aetiologies have been found particularly that due to long term Nitrofurantoin. We report the observation of a 57 year old patient, a cigarette smoker, in whom the diagnosis of PID was made after histological examination of a lung biopsy. Based on this observation the pathogenesis and possible different aetiologies of PID are discussed.
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