A diaplacentar transmission of the Masugi nephritis or the evocation of a clinical picture similar to the congenital glomerulonephritis could not be achieved in rabbits. Also, the juxtaglomerular index-values of the experimental group did not show a significant difference referred to the control group.
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[Myasthenia gravis-Gender aspects and family planning].
Nervenarzt
April 2024
Department of Neurology, Neuroscience Clinical Research Center (NCRC) and Integrated Myasthenia Gravis Center, Charité - Universitätsmedizin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.
Article Synopsis
- Gender differences can affect the diagnosis, treatment, and long-term outcomes of myasthenia gravis (MG), particularly since women are often diagnosed during childbearing years.
- A literature review highlights that these differences include clinical factors and antibody status, with pregnancy generally being safe for MG patients and good outcomes expected for mothers and infants.
- Close monitoring during pregnancy is crucial to quickly address any potential issues caused by maternal antibodies, emphasizing the need for thorough medical advice and teamwork among healthcare providers for patients planning to have children.
Diagnosis: The diagnosis of Graves' disease is mainly based on ultrasonography and laboratory diagnostics. This includes the determination of the TSH value and the peripheral thyroid hormones. TSH receptor antibody (TRAb) measurement is highly sensitive and specific for the detection of Graves' disease (GD) and helps to distinguish from autoimmune thyroiditis (AIT).
View Article and Find Full Text PDFCharacterization of a Cytopathogenic Reporter CSFV.
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Cytopathogenic (cp) pestiviruses frequently emerge in cattle that are persistently infected with the bovine viral diarrhea virus (BVDV) as a consequence of RNA recombination and mutation. They induce apoptosis in infected tissue cultures, are highly attenuated in the immunocompetent host, and unable to establish persistent infections after diaplacental infections. Cp strains of BVDV have been used as naturally attenuated live vaccines and for species-specific plaque reduction tests for the indirect serological detection of BVDV.
View Article and Find Full Text PDFLow prevalence of porcine circovirus type 2 infections in farrowing sows and corresponding pre-suckling piglets in southern German pig farms.
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Background: Epidermolysis bullosa acquisita (EBA) is a severe autoimmune skin disease characterized by autoantibodies to type VII collagen, the major component of anchoring fibrils. In this and other autoimmune bullous dermatoses, specific autoantibody detection systems are not only of diagnostic use but also allow monitoring of circulating and skin-bound autoantibodies during the course of the disease. However, little is known about their natural clearance rates in these different compartments.
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