Structure and innervation of paraventricular and supraoptic hypothalamic nuclei, thyroid gland, adrenals and ovaries were studied by methods of histochemistry and electron microscopy in guinea pigs following chronic treatment with lead acetate in doses 50.10 and 0.1 mg/kg per day. A certain dependence between sympathoadrenal system activity and morphofunctional parameters of the endocrine organs studied was established, which is determined by the pathogenic factor dose and duration of effect.
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