We recently constructed a comparative genetic map of the rat, mouse and human genomes based on information obtained from several databases. In this study, we performed chromosomal assignments of 29 rat genes with somatic cell hybrid clones, in order to clarify and extend the conserved regions in the rat and mouse genomes. As a result, the conserved regions were extended by 89 cM. Together with our previous report, the length of the conserved regions in the rat and mouse spans 847 cM on the mouse linkage map, indicating that 53% of the mouse genome is covered by homologous regions in the rat. In addition, four conserved regions were newly revealed. The method described in this study appears to be simple and efficient for constructing a whole genome comparative map of the rat and mouse.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1538/expanim.47.83 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Microbial Communities in Agave Fermentations Vary by Local Biogeographic Regions.
Environ Microbiol Rep
February 2025
Departamento de Ingeniería Genética, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Unidad Irapuato, Irapuato, Mexico.
The production of traditional agave spirits in Mexico, such as mezcal, involves a process that uses environmental microorganisms to ferment the cooked must from agave plants. By analysing these microorganisms, researchers can understand the dynamics of microbial communities at the interface of natural and human-associated environments. This study involved 16S and ITS amplicon sequencing of 99 fermentation tanks from 42 distilleries across Mexico.
View Article and Find Full Text PDFGenetically and chemically intraspecific variations of Ficus hirta provide novel insights into its protection and utilization.
BMC Plant Biol
January 2025
School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China.
Background: Radix Fici Hirtae, the dry root of Ficus hirta, is a famous ethnomedicine and food that has been widely used by Yao and Zhuang nationalities in southern China for its potent antitumor, antifungal, and hepatoprotective effects. Recently, owing to over-exploitation and habitat destruction, F. hirta has been pushed to the brink of depletion.
View Article and Find Full Text PDFExternal validation of a multivariable prediction model for positive resection margins in breast-conserving surgery.
BMC Res Notes
January 2025
Department of Surgery, Department of Clinical Sciences, Division of Surgery, Skåne University Hospital, Lund University, Lund, Sweden.
Objectives: Positive resection margins after breast-conserving surgery (BCS) most often demands a repeat surgery. To preoperatively identify patients at risk of positive margins, a multivariable model has been developed that predicts positive margins after BCS with a high accuracy. This study aimed to externally validate this prediction model to explore its generalizability and assess if additional preoperatively available variables can further improve its predictive accuracy.
View Article and Find Full Text PDFA dataset of forest regrowth in globally key deforestation regions.
Sci Data
January 2025
Key Laboratory of Humid Subtropical Eco-Geographical Process of Ministry of Education, School of Geographical Sciences, Fujian Normal University, Fuzhou, 350117, China.
Deforestation-induced forest loss largely affects both the carbon budget and ecosystem services. Subsequent forest regrowth plays a crucial role in ecosystem restoration and carbon replenishment. However, there is an absence of comprehensive datasets explicitly delineating the forest regrowth following deforestation.
View Article and Find Full Text PDFExtreme migratory connectivity and apparent mirroring of non-breeding grounds conditions in a severely declining breeding population of an Afro-Palearctic migratory bird.
Sci Rep
January 2025
British Trust for Ornithology, The Nunnery, Thetford, Norfolk, IP24 2PU, UK.
Understanding the distribution of breeding populations of migratory animals in the non-breeding period (migratory connectivity) is important for understanding their response to environmental change. High connectivity (low non-breeding population dispersion) may lower resilience to climate change and increase vulnerability to habitat loss within their range. Very high levels of connectivity are reportedly rare, but this conclusion may be limited by methodology.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!