The authors present an analysis of treatment in 141 patients with acute carboxyhemoglobinemia, in 110 of them severe intoxication was noted. All these patients were treated taking into account the degree of intoxication, the period of time elapsed since the moment of the intoxication till the onset of therapy, and the presence of biochemical shifts in blood. In 31 patients being in an extremely poor comatous state with considerable disorders in gas balance, persistant hemodynamic disturbances and manifest humoral shifts a parallel perfusion with extracorporeal oxygenation of blood was performed with medical drug therapy in the background. The immediate effect was found to be quite favourable, however, 19 patients died in different terms as a result of subsequent complications, most frequently due to pneumonia and meningoencephalitis.
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