Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1086/598358 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Synthesis, characterization and biological profile of some new dihydropyrimidinone derivaties.
Heliyon
January 2025
Department of Pharmaceutical Chemistry, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan, 44000.
Objective: The rise of drug-resistant bacteria, viruses, and fungi has prompted the search for new drugs without cross-resistance to current treatments. As a result, the aim of this research was to synthesize various types of dihydropyrimidinones heterocyclic compounds and screened them for their antibiotic properties.
Methodology: Newly synthesized dihydropyrimidinone derivatives were characterized spectroscopically using proton NMR (HNMR), and FT-IR.
Evaluation of the antibacterial properties of four bioactive biomaterials for chronic wound management.
Future Microbiol
January 2025
Department of Biological Sciences, Missouri University of Science and Technology, Rolla, MO, USA.
Aim: Chronic wound infections present a prevalent medical issue and a multifaceted problem that significantly impacts healthcare systems worldwide. Biofilms formed by pathogenic bacteria are fundamental virulence factors implicated in the complexity and persistence of bacterial-associated wound infections, leading to prolonged recovery times and increased risk of infection. This study aims to investigate the antibacterial effectiveness of commonly employed bioactive wound healing compositions with a particular emphasis on their effectiveness against common bacterial pathogens encountered in chronic wounds - , , and to identify optimal wound product composition for managing chronic wound infections.
View Article and Find Full Text PDFQuantitative Characterization of Localized Hydrophobicity Surrounding Polymer Particle Surfaces for Aqueous Antibacterial Colloids.
Langmuir
January 2025
Department of Chemical Engineering, Tohoku University, Sendai, Miyagi 9808579, Japan.
Aqueous antibacterial colloids are potential agents that kill bacteria via physical contact. Conventionally, antibacterial agents are designed to be small, cationic, or hydrophobic. However, hydrophobic materials easily aggregate in aqueous media, drastically inhibiting their activity.
View Article and Find Full Text PDFCharacterization of antimicrobial properties of TroH2A-29 peptide from golden pompano (Trachinotus ovatus).
Dev Comp Immunol
January 2025
Key Laboratory of Marine Genetics and Breeding, Ministry of Education/ Key Laboratory of Tropical Aquatic Germplasm of Hainan Province, Sanya Oceanographic Institution, Ocean University of China, Qingdao, 266003, Shandong, China. Electronic address:
Antimicrobial peptides (AMPs) are small, potent molecules that serve as a crucial first line of defense across a wide range of organisms, including fish. In this study, we investigated the antimicrobial properties of a novel peptide, spanning residues 52 to 80 of the full-length histone H2A protein, comprising a total of 29 amino acids. This peptide, designated as Histone H2A-29 (TroH2A-29), was derived from the golden pompano (Trachinotus ovatus) and evaluated for its activity against both Gram-positive bacteria, Lactococcus garvieae and Staphylococcus epidermidis, and Gram-negative bacteria, Vibrio alginolyticus and Vibrio harveyi.
View Article and Find Full Text PDFAssessment of bacteriological and immunological markers in urinary tract infection and the effect of antibiotics on the isolated bacteria.
Cell Mol Biol (Noisy-le-grand)
January 2025
Laboratory of Plant Improvement and Valorization of Agro-resources, National School of Engineers of Sfax, University of Sfax, Sfax LR.16ES20, Tunisia.
Urinary tract infections (UTIs) are recognized as the second most common medical condition, following respiratory infections. Despite the availability of numerous efficacious antibiotics for the management of UTIs, the rising incidence of bacterial resistance presents significant challenges in the treatment of these infections. Bacteria are endowed with the ability to reproduce and develop resistance mechanisms against antibiotics.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!