Atopic diseases and among them bronchial asthma seem to be the worldwide epidemic of the end of the 20th century and this tendency may continue even in the 3rd millenium. The main factors and periods which are important in the genesis of bronchial asthma are the following: genetic influences; intrauterine sensitization; factors in the perinatal life; influences in infancy; environmental factors in childhood; bronchial asthma and "western lifestyle"; prevention of further developing of atopic diseases.
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