AI Article Synopsis
- Buruli ulcer is a severe skin disease caused by the bacteria Mycobacterium ulcerans, mainly found in central/west Africa and Australia.
- A 2.5-year-old boy from Angola was hospitalized with severe malnutrition and a large ulcer on his chest, along with other health issues like anemia and intestinal parasites.
- Treatment included surgical removal of the affected skin, a skin graft, and antibiotic therapy, leading to a successful recovery after six months; this is the first documented case of Buruli ulcer in Angola.
Article Abstract
Buruli ulcer, caused by Mycobacterium ulcerans, is a chronic ulcerative skin disease, found predominantly in central and west Africa and Australia. A boy of 2.5 years of age from Angola was admitted to our hospital with severe kwashiokor and a large ulcer with undermined edges on the left side of the thorax. Further examination revealed anaemia, hypoproteinaemia, bacterial superinfection of the ulcer and intestinal parasites. Histological analysis showed acid-fast bacilli and histopathological changes typical of Buruli ulcer. M. ulcerans was detected by PCR and culture. The patient was treated by surgical excision of diseased skin, followed by split-skin grafting. He also received antibiotic therapy (ciprofloxacin, clarithromycin, rifabutin, and dapsone). After six months, the child was discharged from hospital in good condition. This is the first published case of Buruli ulcer from Angola.
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| http://dx.doi.org/10.1046/j.1365-3156.1998.00225.x | DOI Listing |
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