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Failure modes and interaction mechanisms of tunnel under active landslide conditions.
Sci Rep
January 2025
China Academy of Railway Sciences Co. Ltd, Beijing, 100081, China.
The construction of tunnels can easily trigger the reactivation of old landslide bodies, posing a threat to the transportation safety. In this study, using methods such as engineering geological investigation, slope deformation monitoring, deep displacement monitoring, and numerical simulation, the interaction between landslides and tunnels was investigated from the perspective of landslide deformation and failure characteristics. The Walibie Tunnel (WLBT) of Shangri-La to Lijiang (XL) expressway was taken as an example.
View Article and Find Full Text PDFStable Gastric Pentadecapeptide BPC 157 as Therapy After Surgical Detachment of the Quadriceps Muscle from Its Attachments for Muscle-to-Bone Reattachment in Rats.
Pharmaceutics
January 2025
Department of Pharmacology, School of Medicine, University of Mostar, 88000 Mostar, Bosnia and Herzegovina.
Background: This is a novel rat study using native peptide therapy, focused on reversing quadriceps muscle-to-bone detachment to reattachment and stable gastric pentadecapeptide BPC 157 per-oral therapy for shared muscle healing and function restoration.
Methods: Pharmacotherapy recovering various muscle, tendon, ligament, and bone lesions, and severed junctions (i.e.
Contradictory Mechanisms of rheumatoid arthritis and hepatitis B virus infection activation.
Heliyon
January 2025
Department of Rheumatology, Wuxi Hospital of Traditional Chinese Medicine, Wuxi, 214000, Jiangsu, China.
Rheumatoid arthritis (RA) is associated with a high rate of hepatitis B virus (HBV) infection. A large proportion of HBV reactivation may occur in RA patients after immunosuppression treatment, while fulminant hepatitis may occur in severe cases. Immunosuppressants are fundamental medications for the treatment of RA but carry the risk of inducing HBV reactivation.
View Article and Find Full Text PDFTracing the relationship between the upper plate earthquake cycle and megathrust slip, the Atacama fault system in Northern Chile.
Sci Rep
January 2025
Geology Department Middlebury College, Middlebury, Vermont, 05753, USA.
Inland-normal faulting is recognised as an important process following large subduction earthquakes. The lack of data limits the understanding of how normal fault reactivation relates to the subduction earthquake cycle. We characterised the palaeoseismology of the Atacama fault system (AFS) in the Chilean subduction zone.
View Article and Find Full Text PDFIdentification of hypothermia-inducing neurons in the preoptic area and activation of them by isoflurane anesthesia and central injection of adenosine.
J Physiol Sci
January 2025
Department of Physiology, Graduate School of Medical and Dental Sciences, Kagoshima University, Sakuragaoka 8-35-1, 890-8544, Kagoshima, Japan. Electronic address:
Hibernation and torpor are not passive responses caused by external temperature drops and fasting but are active brain functions that lower body temperature. A population of neurons in the preoptic area was recently identified as such active torpor-regulating neurons. We hypothesized that the other hypothermia-inducing maneuvers would also activate these neurons.
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